Abstract
The total number of COVID-19 positive cases in Latvia has escalated rapidly since October 2020, peaking in late December 2020 and early January 2021. Children generally develop COVID-19 more mildly than adults; however, it can be complicated by multisystem inflammatory syndrome in children (MIS-C). This case study aims were to assess demographic characteristics and the underlying medical conditions, and clinical, investigative and treatment data among 13 MIS-C patients using electronic medical records. All 13 had acute illness or contact with someone who was COVID-19 positive two to six weeks before MIS-C onset. Only five of the 13 were symptomatic during the acute COVID-19 phase. The median age was 8.8 years; 11/13 patients were male, 10/13 had been previously healthy, and all 13 patients tested positive for SARS-CoV-2 by RT-PCR or antibody testing. The most commonly involved organ systems were the gastrointestinal (13/13), hematologic (13/13), cardiovascular (13/13), skin and mucosa (13/13), and respiratory (12/13) ones. The median hospital stay was 13 (interquartile range, 11 to 18) days; 7/13 patients received intensive care, 6/13 oxygen support, and 5/13 received inotropic support. No deaths occurred. During the current pandemic, every child with a fever should have a clearly defined epidemiological history of COVID-19, a careful clinical assessment of possible multiple organ-system involvement, with a special focus on children with severe abdominal pain and/or skin and mucocutaneous lesions.
Original language | English |
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Pages (from-to) | 363-373 |
Number of pages | 11 |
Journal | CLINICS AND PRACTICE |
Volume | 11 |
Issue number | 2 |
DOIs | |
Publication status | Published - 11 Jun 2021 |
Keywords*
- COVID-19
- SARS-CoV-2
- multisystem inflammatory syndrome in children (MIS-C)
Field of Science*
- 3.2 Clinical medicine
- 1.6 Biological sciences
- 3.3 Health sciences
Publication Type*
- 1.1. Scientific article indexed in Web of Science and/or Scopus database