Case series of variable acute appendicitis in children with sars-cov-2 infection

Arnis Engelis, Liene Smane, Jana Pavare, Astra Zviedre, Timurs Zurmutai, Marisa M. Berezovska, Jurijs Bormotovs, Mohit Kakar (Corresponding Author), Amulya K. Saxena, Aigars Petersons

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Abstract

This case series study consists of six children, aged 5–16 years, admitted to a centralized tertiary paediatric hospital serving a population of 1.9 million with acute appendicitis in the setting of SARS-CoV-2 infection. From the beginning of the pandemic in March 2020 until August 2021, 121 COVID-19-positive children were admitted to the hospital. A total of 49 (40.5%) of these patients presented with gastrointestinal symptoms, of which six were diagnosed with acute appendicitis. Five underwent an appendectomy, while one was treated conservatively. To date, it has been reported that appendicitis may have a plausible association with SARS-CoV-2 infection in children. With COVID-19 cases rising, every medical specialist, including all paediatric surgeons, must be ready to treat common acute diseases with SARS-CoV-2 infection as a comorbidity. Providers should consider testing for this infection in paediatric patients with severe gastrointestinal symptoms. Non-surgical treatment of acute appendicitis in children may gain new importance during and after the COVID-19 pandemic. Further studies are needed to prove the link of causality between COVID-19 and acute appendicitis in children.

Original languageEnglish
Article number1207
JournalChildren
Volume8
Issue number12
DOIs
Publication statusPublished - Dec 2021

Keywords*

  • COVID-19
  • Paediatric abdominal pain
  • Paediatric appendicitis
  • SARS-CoV-2

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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