Abstract
Objectives
Exposure to dangerously increased doses of radiation can cause severe damage to human body and its tissues. It is suggested that exposure to extremely incresed doses of radiation can cause migration of human lens fibers towards the posterior cortex of the lens and cause formation of posterior subcapsular cataract. This research was carried out to evalute whether Chornobyl ex clean-up workers have a higher prevalence of posterior subcapsular cataract.
Materials and methods
The research included 15 eyes of healthy individuals, 15 eyes of Chornobyl ex clean-up workers who worked only in the city and 15 eyes of Chornobyl ex clean-up workers who worked on the roof of the reactor. A one-way analysis of covariance (ANCOVA) was conducted to compare lens thickness, posterior cortex thickness, and the percentage of the posterior cortex occupying the whole lens across research groups. Age was included as a covariate to statistically control for its potential influence on the dependent variables. Following the ANCOVA, Tukey's Honestly Significant Difference (HSD) test was used for post-hoc comparisons among the research groups. All statistical analyses were performed using Jamovi statistical software (https://www.jamovi.org) with a significance level of α = 0.05.
Results
Tukey's Honestly Significant Difference (HSD) test showed that there is a statistically significant difference in posterior lens cortex thickness and the percentage it occupies in the whole lens between all of the groups (p<0,001). There was also a statistically significant difference in the actual lens thickness between the groups (p=0,008).
Conclusions
Our research shows that there is a significant difference in lens morphology in patients with exposure to extremely increased doses of radiation when compared to healthy individuals and that these high dose radiation affected patients have an increased prevalence of posterior subcapsular cataract.
Exposure to dangerously increased doses of radiation can cause severe damage to human body and its tissues. It is suggested that exposure to extremely incresed doses of radiation can cause migration of human lens fibers towards the posterior cortex of the lens and cause formation of posterior subcapsular cataract. This research was carried out to evalute whether Chornobyl ex clean-up workers have a higher prevalence of posterior subcapsular cataract.
Materials and methods
The research included 15 eyes of healthy individuals, 15 eyes of Chornobyl ex clean-up workers who worked only in the city and 15 eyes of Chornobyl ex clean-up workers who worked on the roof of the reactor. A one-way analysis of covariance (ANCOVA) was conducted to compare lens thickness, posterior cortex thickness, and the percentage of the posterior cortex occupying the whole lens across research groups. Age was included as a covariate to statistically control for its potential influence on the dependent variables. Following the ANCOVA, Tukey's Honestly Significant Difference (HSD) test was used for post-hoc comparisons among the research groups. All statistical analyses were performed using Jamovi statistical software (https://www.jamovi.org) with a significance level of α = 0.05.
Results
Tukey's Honestly Significant Difference (HSD) test showed that there is a statistically significant difference in posterior lens cortex thickness and the percentage it occupies in the whole lens between all of the groups (p<0,001). There was also a statistically significant difference in the actual lens thickness between the groups (p=0,008).
Conclusions
Our research shows that there is a significant difference in lens morphology in patients with exposure to extremely increased doses of radiation when compared to healthy individuals and that these high dose radiation affected patients have an increased prevalence of posterior subcapsular cataract.
| Original language | English |
|---|---|
| Pages | 228 |
| Publication status | Published - 24 Mar 2025 |
| Event | RSU Research week 2025 - 16 Dzirciema Street, Riga, Rīga, Latvia Duration: 24 Mar 2025 → 28 Mar 2025 https://rw2025.rsu.lv/ https://rw2025.rsu.lv/knowledge-use-practice https://rw2025.rsu.lv/places https://rw2025.rsu.lv/society-health-welfare |
Conference
| Conference | RSU Research week 2025 |
|---|---|
| Abbreviated title | RW2025 |
| Country/Territory | Latvia |
| City | Rīga |
| Period | 24/03/25 → 28/03/25 |
| Other | International Conference on Medical and Health Research. RSU Scientific Conference |
| Internet address |
Field of Science*
- 3.2 Clinical medicine
Publication Type*
- 3.4. Other publications in conference proceedings (including local)
