Change of biomechanical parameters in the lower jaws of rabbits with experimental osteoporosis after implantation of calcium-phosphate bioceramic material in the greater trochanter region

Girts Salms, Vladislavs Ananjevs, Vladimirs Kasyanovs, Andrejs Skagers, Ilze Salma, Janis Vetra, Vita Zalite, Liga Stipniece, Sandris Petronis

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Investigation of biomechanical properties of the rabbit bone tissue from a corner of the lower jaw was done. Experimental osteoporosis was induced by ovariectomy and following injections of methylprednisolone. The defects in the greater trochanter region was created and filled with granules of a hydroxyapatite and tricalcium phosphate (HAP/TCP 30/70) or HAP/TCP 30/70 together with 5% strontium ranelate. After 3 month animals were euthanased, squared samples have been cut out from a corner of the lower jaw and tested on a bend. Results of research show, that the corner of a lower jaw in rabbit becomes more rigid after filling of defects in the greater trochanter region with granules of a hydroxyapatite and tricalcium phosphate (HAP/TCP 30/70) or granules together with strontium ranelate. The ultimate strain for the bone tissue in the 2nd and 3rd group is less, than for control group. Thus, local uses calcium - phosphatic bioceramic material around the greater trochanter region improves biomechanical parameters of a bone tissue in the lower jaw of animals.

Original languageEnglish
Title of host publicationEngineering Materials and Tribology XXV
EditorsDagnija Loca
PublisherTrans Tech Publications Ltd
Pages224-228
Number of pages5
ISBN (Print)9783035710724
DOIs
Publication statusPublished - 2017
Event25th International Baltic Conference of Engineering Materials and Tribology – BALTMATTRIB - Riga, Latvia
Duration: 3 Nov 20164 Nov 2016
Conference number: 25

Publication series

NameKey Engineering Materials
Volume721 KEM
ISSN (Print)1013-9826
ISSN (Electronic)1662-9795

Conference

Conference25th International Baltic Conference of Engineering Materials and Tribology – BALTMATTRIB
CountryLatvia
CityRiga
Period3/11/164/11/16

Keywords

  • Bioceramic
  • Biomechanics
  • Lower jaw
  • Osteoporosis
  • Rabbit

Field of Science

  • 2.6 Medical engineering
  • 3.1 Basic medicine

Publication Type

  • 3.1. Articles or chapters in proceedings/scientific books indexed in Web of Science and/or Scopus database

Fingerprint Dive into the research topics of 'Change of biomechanical parameters in the lower jaws of rabbits with experimental osteoporosis after implantation of calcium-phosphate bioceramic material in the greater trochanter region'. Together they form a unique fingerprint.

Cite this