Changing MCC type (without composition change) to alter the mechanical properties of tablets obtained

Valentyn Mohylyuk; Kirils Kukuls; Alīna Jaroslava Frolova; Elzbieta Maria Buczkowska; Julia Shmyrova

doi:10.13140/RG.2.2.11956.82563

Changing MCC type (without composition change) to alter the mechanical properties of tablets obtained

Valentyn Mohylyuk (Corresponding Author)
, Kirils Kukuls
, Alīna Jaroslava Frolova
, Elzbieta Maria Buczkowska
, Julia Shmyrova

Research output: Contribution to conference › Poster

Original language	English
Number of pages	1
DOIs	https://doi.org/10.13140/RG.2.2.11956.82563
Publication status	Published - 1 Jun 2026
Event	The Compaction Simulation Forum 2026 - Lisbon, Portugal Duration: 1 Jun 2026 → 3 Jun 2026 https://www.compactionsimulation.com/

Forum

Forum	The Compaction Simulation Forum 2026
Abbreviated title	CSF 2026
Country/Territory	Portugal
City	Lisbon
Period	1/06/26 → 3/06/26
Internet address	https://www.compactionsimulation.com/

Keywords*

tablets
granulation
roll compaction
roll compaction force
microcrystalline cellulose
mechanical properties

Field of Science*

1.4 Chemical sciences
2.5 Materials engineering
3.1 Basic medicine

Publication Type*

3.4. Other publications in conference proceedings (including local)

Access to Document

10.13140/RG.2.2.11956.82563

1 Active
2 Finished

Direct compression of highly used excipients in pharmaceutical tablet manufacturing: calcium phosphate dibasic anhydrous and microcrystalline cellulose
Kukuls, K. (Participant) & Mohylyuk, V. (Project leader)
1/08/23 → 31/07/27
Project: Projects outside RSU
Effect of diluent type on the acetaminophen release from tablets under simulated fasted and fed conditions
Frolova, A. J. (Project leader), Gurkina, K. (Expert), Kukuls, K. (Expert) & Mohylyuk, V. (Supervisor)
3/11/25 → 30/04/26
Project: Student projects
Investigation of the effect of microcrystalline cellulose type and roll compaction force on the properties of granules and tablets containing a high dose of poorly compactible substance
Mohylyuk, V. (Project leader) & Kukuls, K. (Leading expert)
14/10/25 → 28/02/26
Project: Contract research › R&D project

Cite this

@conference{03e5b3fb904e47ec8854c4d46575ee8f,

title = "Changing MCC type (without composition change) to alter the mechanical properties of tablets obtained",

keywords = "tablets, granulation, roll compaction, roll compaction force, microcrystalline cellulose, mechanical properties",

author = "Valentyn Mohylyuk and Kirils Kukuls and Frolova, \{Alīna Jaroslava\} and Buczkowska, \{Elzbieta Maria\} and Julia Shmyrova",

year = "2026",

month = jun,

day = "1",

doi = "10.13140/RG.2.2.11956.82563",

language = "English",

note = "The Compaction Simulation Forum 2026, CSF 2026 ; Conference date: 01-06-2026 Through 03-06-2026",

url = "https://www.compactionsimulation.com/",

}

TY - CONF

T1 - Changing MCC type (without composition change) to alter the mechanical properties of tablets obtained

AU - Mohylyuk, Valentyn

AU - Kukuls, Kirils

AU - Frolova, Alīna Jaroslava

AU - Buczkowska, Elzbieta Maria

AU - Shmyrova, Julia

PY - 2026/6/1

Y1 - 2026/6/1

KW - tablets

KW - granulation

KW - roll compaction

KW - roll compaction force

KW - microcrystalline cellulose

KW - mechanical properties

U2 - 10.13140/RG.2.2.11956.82563

DO - 10.13140/RG.2.2.11956.82563

M3 - Poster

T2 - The Compaction Simulation Forum 2026

Y2 - 1 June 2026 through 3 June 2026

ER -

Changing MCC type (without composition change) to alter the mechanical properties of tablets obtained

Forum

Keywords*

Field of Science*

Publication Type*

Access to Document

Projects

Direct compression of highly used excipients in pharmaceutical tablet manufacturing: calcium phosphate dibasic anhydrous and microcrystalline cellulose

Effect of diluent type on the acetaminophen release from tablets under simulated fasted and fed conditions

Investigation of the effect of microcrystalline cellulose type and roll compaction force on the properties of granules and tablets containing a high dose of poorly compactible substance

Cite this