Characterization of clinical isolates of Enterococci indicates drifting trends in anti-microbial resistance: a four year Latvian perspective

Aigars Reinis, Nityanand Jain, Tatjana Obidenova, Inese Jansone, Dagnija Straupmane, Janis Meisters

Research output: Contribution to conferenceAbstractpeer-review


Objectives The present study aims to present the current trends in emergence of multidrug resistant nosocomial strains of Enterococci species at P.Stradiņš Hospital in Latvia.

Materials and Methods Bacterial isolates were collected from 2,478 patients admitted in different departments in Paul Stradins Clinical University Hospital over the course of four years from 2017 to 2020. All clinical samples like pus, blood, urine etc. were inoculated on appropriate media and species identification was done using Vitek2 analyzer or MALDI-TOFF. Antimicrobial susceptibility was assessed disk diffusion test according latest EUCAST recommendations. Statistical analysis was done using Excel and R.

Results E. faecalis was the most common isolated species followed by E. faecium with both species showing a significant increase (P < 0.05) in occurrence in Period 2 (2019-20) when compared with Period 1 (2017-18). Co-infection by both species also saw a significant rise in Period 2. Strains of both species showed a decrease in anti-microbial resistance towards ampicillin, ciprofloxacin and norfloxacin. Whilst E. faecalis showed a decrease in resistance towards gentamycin, vancomycin and nitrofurantion, E. faecium showed the opposite trend. A decrease was also noted for Linezolid. Other isolated species like E. avium and E. raffinosus showed increased occurrence as well increase in resistance to tested antibiotics.

Conclusions Drifting trends in anti-microbial resistance pose a substantial challenge in clinical practice. Proper and effective infection control is essential for determining the outcome of clinical treatment along with impeding the emergence of multi-drug resistant strains.
Original languageEnglish
Number of pages1
Publication statusPublished - Nov 2020
EventXV Baltic Congress in Laboratory Medicine - online Zoom, Riga, Latvia
Duration: 6 Nov 20207 Nov 2020
Conference number: 15


CongressXV Baltic Congress in Laboratory Medicine
Abbreviated titleBALM 2020
Internet address


  • Enterococci
  • antimicrobial resistance
  • Nosocomial infection

Field of Science*

  • 3.1 Basic medicine

Publication Type*

  • 3.4. Other publications in conference proceedings (including local)


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