Chronic persistent HHV-6B infection after sulfasalazine-induced DRESS with demonstration of HHV-6 encoded small noncoding RNAs (sncRNAs) in Crohn's-like colitis: Case report

Vincent Descamps; Agnès Gautheret-Dejean; Anne-Laure Pelletier; Pascale Bonnafous; Lydia Deschamps; Bhupesh K Prusty

doi:10.1002/ccr3.3680

Chronic persistent HHV-6B infection after sulfasalazine-induced DRESS with demonstration of HHV-6 encoded small noncoding RNAs (sncRNAs) in Crohn's-like colitis: Case report

Vincent Descamps (Corresponding Author), Agnès Gautheret-Dejean, Anne-Laure Pelletier, Pascale Bonnafous, Lydia Deschamps, Bhupesh K Prusty

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

A sulfasalazine-induced DRESS (Drug Reactivation with Eosinophilia and Systemic Symptoms) was complicated by a Crohn's-like colitis. We demonstrated HHV-6 reactivation with presence of HHV-6 DNA and small noncoding RNA in colonic lesions. This observation confirms the major role of HHV-6 reactivation in DRESS manifestations and the importance of looking for HHV-6 reactivation in DRESS.

Original language	English
Pages (from-to)	841-844
Number of pages	4
Journal	Clinical Case Reports
Volume	9
Issue number	2
DOIs	https://doi.org/10.1002/ccr3.3680
Publication status	Published - Feb 2021
Externally published	Yes

Field of Science*

1.6 Biological sciences
3.1 Basic medicine
3.3 Health sciences

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

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10.1002/ccr3.3680Licence: CC BY

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abstract = "A sulfasalazine-induced DRESS (Drug Reactivation with Eosinophilia and Systemic Symptoms) was complicated by a Crohn's-like colitis. We demonstrated HHV-6 reactivation with presence of HHV-6 DNA and small noncoding RNA in colonic lesions. This observation confirms the major role of HHV-6 reactivation in DRESS manifestations and the importance of looking for HHV-6 reactivation in DRESS.",

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Chronic persistent HHV-6B infection after sulfasalazine-induced DRESS with demonstration of HHV-6 encoded small noncoding RNAs (sncRNAs) in Crohn's-like colitis: Case report. / Descamps, Vincent (Corresponding Author); Gautheret-Dejean, Agnès; Pelletier, Anne-Laure et al.
In: Clinical Case Reports, Vol. 9, No. 2, 02.2021, p. 841-844.

Research output: Contribution to journal › Article › peer-review

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T1 - Chronic persistent HHV-6B infection after sulfasalazine-induced DRESS with demonstration of HHV-6 encoded small noncoding RNAs (sncRNAs) in Crohn's-like colitis

T2 - Case report

AU - Descamps, Vincent

AU - Gautheret-Dejean, Agnès

AU - Pelletier, Anne-Laure

AU - Bonnafous, Pascale

AU - Deschamps, Lydia

AU - Prusty, Bhupesh K

PY - 2021/2

Y1 - 2021/2

N2 - A sulfasalazine-induced DRESS (Drug Reactivation with Eosinophilia and Systemic Symptoms) was complicated by a Crohn's-like colitis. We demonstrated HHV-6 reactivation with presence of HHV-6 DNA and small noncoding RNA in colonic lesions. This observation confirms the major role of HHV-6 reactivation in DRESS manifestations and the importance of looking for HHV-6 reactivation in DRESS.

AB - A sulfasalazine-induced DRESS (Drug Reactivation with Eosinophilia and Systemic Symptoms) was complicated by a Crohn's-like colitis. We demonstrated HHV-6 reactivation with presence of HHV-6 DNA and small noncoding RNA in colonic lesions. This observation confirms the major role of HHV-6 reactivation in DRESS manifestations and the importance of looking for HHV-6 reactivation in DRESS.

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Chronic persistent HHV-6B infection after sulfasalazine-induced DRESS with demonstration of HHV-6 encoded small noncoding RNAs (sncRNAs) in Crohn's-like colitis: Case report

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