Clinical Characteristics of Invasively Ventilated Covid-19 Patients: An Overview of Clinical Experience in Pauls Stradiņš Clinical University Hospital, Rīga, Latvia

Paula Zviedre (Corresponding Author), Darja Smirnova, Anna Klēšmite, Elīna Žuka, Elīna Romanovska, Ģirts Freijs, Oļegs Sabeļņikovs

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Abstract

This retrospective single-centre study was conducted in an intensive care unit (ICU) in Pauls Stradiòð Clinical University Hospital (Rîga, Latvia) between 1 October 2020 and 30 April 2021. The aim was to assess the baseline clinical characteristics and their association with outcome for critically ill coronavirus disease 2019 (COVID-19) patients admitted to the ICU and requiring invasive mechanical ventilation (IMV). Demographic, clinical, laboratory, length-of-stay and mortality data
were collected from medical records. In total, 66 critically ill patients admitted to the ICU were enrolled in this study. 77% were male, and the median age was 65.5 [57.0–70.8] years. Comorbidities included obesity (67.2%), cardiovascular disease (63.6%) and type II diabetes (38.1%). Prone positioning was performed in most cases (68.2%) and one-third (34.8%) of patients required renal replacement therapy during their stay in the ICU. The median time to intubation after hospitalisation was eight [3.3–10.0] days. The median length-of-stay in the ICU was 12 [6.0–18.5] days and the overall mortality among all invasively ventilated patients in the ICU was 86%. In survivors, the duration of time between the onset of symptoms and hospitalisation, and time between the onset of symptoms and intubation, were found to be shorter than in non-survivors.
Original languageEnglish
Pages (from-to)338-345
JournalProceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences
Volume76
Issue number3
DOIs
Publication statusPublished - 1 Jun 2022

Keywords*

  • SARS-CoV-2
  • invasive mechanical ventilation

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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