Clinicopathological features and prognostic factors of gastric cancer

Darja Svirina, Sergejs Isajevs, Inga Bogdanova, Zane Dambe, Georgijs Moisejevs, Armands Sivins, Marcis Leja

Research output: Contribution to journalMeeting Abstractpeer-review


Objective: Gastric cancer (GC) remains the fourth most common type of cancer and the second most common cause of cancer-related death worldwide. The aim of the study was to compare the gastric cancer histopathological subtypes and evaluate the correlation between the histopathological and clinical parameters.
Method: 80 subjects undergoing gastric cancer surgical treatment carcinoma were enrolled in the study. The patients were treated in Riga East University Hospital in 2014. The surgical specimens were grossly and microscopically analyzed. The tumour classification was assessed according to WHO 2010 classification.
Results: Obtained results showed that the tubular adenocarcinoma was observed in 35 % of cases, signet ring cell carcinoma-in 30 %, undiferentiated carcinoma in 20 %, papillary adenocarcinoma in 10 % and mutinous carcinoma in 5 % of cases. The positive correlation between the tumour size and the numbers of metastatic lymph nodes, Bormann classification, gastric atrophy, lymphovascular invasion was observed. Furthermore, the negative correrlation between the Lauren classification and intestinal metaplasia, tumour vascular invasion was observed. In addition, the positive correlation between the Bormann classification and tumour vascular, perineural invasion and the numbers of metastatic lymph nodes was observed.
Conclusion: The tumour histopathological characteristics correlated with the clinical course and prognosis.

Field of Science*

  • 3.1 Basic medicine
  • 3.2 Clinical medicine

Publication Type*

  • 3.3. Publications in conference proceedings indexed in Web of Science and/or Scopus database


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