Congenital systemic abnormalities and other inborn ocular pathologies in children with congenital cataracts

Kristiāna Čačka, Sandra Valeiņa, Elīna Skaistkalne, Guna Laganovska

Research output: Contribution to conferenceAbstractpeer-review


A congenital cataract is a major cause of childhood blindness. Although, most congenital cataracts remain idiopathic, in some cases a child can have more than one inborn pathology, neither ocular nor systemic. A congenital cataract is associated with ocular abnormalities in 27% of cases and with systemic abnormalities in 22% of cases (Khokhar SK et al, 2017). Observing and understanding the whole child's health condition is not only essential for the ophthalmologist, but also for whole care providers as a general practitioner, pediatrician, etc. The retrospective study was held at Children's Clinical University Hospital l (Riga, Latvia). A total of 110 medical records from patients with congenital cataracts were observed. IBM SPSS Statistics version 25.0 was used to process data. Out of the 110 patients included in this study 54,5% (n=60) had bilateral cataracts, 45,5% (n=50) had unilateral cataracts. The majority of patients 49,1% (n=54) had developed an early congenital cataract. Out of all patients, 32,7% (n=36) also had systemic congenital abnormalities. The main part (n=8) of inborn pathologies was preterm birth. Almost one third – 27,3 % (n=30) of all patients had other congenital ocular diseases. 43,3% (n=13) had anterior segment abnormalities as aniridia or microcornea, followed by 23,3% (n=7) retinal pathologies and 13,3% (n=4) ocular nerve defects. Out of all patients with bilateral cataracts, 41,6% (n=25) had been born with other inborn pathologies. There is a very weak correlation between the development of bilateral cataract and other ocular or systemic abnormalities (p>0.005). A great part of children with congenital cataracts also was born with other congenital systemic or ocular abnormalities. Of other congenital ocular pathologies majority was liked with anterior segment development defects. Although there is a correlation between the development of bilateral congenital cataracts and other systemic or ocular inborn abnormalities, this correlation is not statistically significant
Original languageEnglish
Publication statusPublished - 24 Mar 2021
EventRSU Research week 2021: Knowledge for Use in Practice - Rīga, Latvia
Duration: 24 Mar 202126 Mar 2021


ConferenceRSU Research week 2021: Knowledge for Use in Practice
Abbreviated titleRW2021
Internet address

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 3.4. Other publications in conference proceedings (including local)


Dive into the research topics of 'Congenital systemic abnormalities and other inborn ocular pathologies in children with congenital cataracts'. Together they form a unique fingerprint.

Cite this