In experiments on the preparation of adrenals in situ in eviscerated spinal cats according to the method of Feldberg and Minz (1931) it was shown that amphetamine, but not ephedrine, evoked the release of catecholamines from the adrenals. This action was not influenced by neostigmine and was blocked by hexamethonium. It is concluded that the catecholamine-releasing action of amphetamine is a cholinomimetic one and is due to the direct influence of this drug on the cholinoreceptors.
Field of Science*
- 3.1 Basic medicine
- 1.1. Scientific article indexed in Web of Science and/or Scopus database