Abstract
Background and Objectives. It has been shown that dermoscopy improves diagnostic accuracy of a clinician. Nevertheless, data on dynamics of dermoscopically seen structures and treatment impact on them is scarce; therefore, we chose to monitor shiny white streaks (SWS), during topical treatment of actinic keratoses (AK).
Materials and Methods. AK lesions located on face or scalp were treated with either topical 5% 5-fluorouracil cream (5FU) or daylight photodynamic therapy with methyl aminolevulinate (DL-PDT). Dermoscopic assessments were performed before start of therapy, at peak inflammatory phase and one-month post-treatment (Follow-up visit).
Results. Of 38 lesions followed, before start of therapy SWS were present in 18 (47%) lesions. In five cases (13%) SWS remained present through all visits. In three cases (8%) SWS were present until the Follow-up visit. In ten (26%) AKs SWS disappeared at the peak inflammatory phase, but in four (11%) of those SWS later reappeared. Of 20 (53%) lesions without SWS at the first visit, only one (3%) developed SWS at a Follow-up visit.
Conclusions. SWS seem to be variable structures that can be unseen in lesions with therapy induced inflammation, disappear following topical treatment of AK and sometimes appear for the first time post-treatment. It could be important to take into consideration the dynamics of SWS when assessing their presence.
Materials and Methods. AK lesions located on face or scalp were treated with either topical 5% 5-fluorouracil cream (5FU) or daylight photodynamic therapy with methyl aminolevulinate (DL-PDT). Dermoscopic assessments were performed before start of therapy, at peak inflammatory phase and one-month post-treatment (Follow-up visit).
Results. Of 38 lesions followed, before start of therapy SWS were present in 18 (47%) lesions. In five cases (13%) SWS remained present through all visits. In three cases (8%) SWS were present until the Follow-up visit. In ten (26%) AKs SWS disappeared at the peak inflammatory phase, but in four (11%) of those SWS later reappeared. Of 20 (53%) lesions without SWS at the first visit, only one (3%) developed SWS at a Follow-up visit.
Conclusions. SWS seem to be variable structures that can be unseen in lesions with therapy induced inflammation, disappear following topical treatment of AK and sometimes appear for the first time post-treatment. It could be important to take into consideration the dynamics of SWS when assessing their presence.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of the 62nd International Scientific Conference of Daugavpils University |
| Subtitle of host publication | Part A. Natural Sciences |
| Editors | Irēna Kokina |
| Place of Publication | Daugavpils |
| Publisher | Daugavpils University |
| Pages | 139-143 |
| ISBN (Print) | 978-9984-14-925-7 |
| Publication status | Published - 2020 |
| Event | 62nd International Scientific Conference of Daugavpils University - Daugavpils, Latvia Duration: 28 May 2020 → 29 May 2020 Conference number: 62 |
Conference
| Conference | 62nd International Scientific Conference of Daugavpils University |
|---|---|
| Country/Territory | Latvia |
| City | Daugavpils |
| Period | 28/05/20 → 29/05/20 |
| Other | Daugavpils Universitātes 62. starptautiskā zinātniskā konference |
Keywords*
- shiny white streaks
- chrysalis structures
- actinic keratosis
- dermoscopy
Field of Science*
- 3.2 Clinical medicine
Publication Type*
- 3.2. Articles or chapters in other proceedings other than those included in 3.1., with an ISBN or ISSN code