Dermoscopic monitoring of shiny white streaks during topical treatment of actinic keratosis

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Background and Objectives. It has been shown that dermoscopy improves diagnostic accuracy of a clinician. Nevertheless, data on dynamics of dermoscopically seen structures and treatment impact on them is scarce; therefore, we chose to monitor shiny white streaks (SWS), during topical treatment of actinic keratoses (AK).
Materials and Methods. AK lesions located on face or scalp were treated with either topical 5% 5-fluorouracil cream (5FU) or daylight photodynamic therapy with methyl aminolevulinate (DL-PDT). Dermoscopic assessments were performed before start of therapy, at peak inflammatory phase and one-month post-treatment (Follow-up visit).
Results. Of 38 lesions followed, before start of therapy SWS were present in 18 (47%) lesions. In five cases (13%) SWS remained present through all visits. In three cases (8%) SWS were present until the Follow-up visit. In ten (26%) AKs SWS disappeared at the peak inflammatory phase, but in four (11%) of those SWS later reappeared. Of 20 (53%) lesions without SWS at the first visit, only one (3%) developed SWS at a Follow-up visit.
Conclusions. SWS seem to be variable structures that can be unseen in lesions with therapy induced inflammation, disappear following topical treatment of AK and sometimes appear for the first time post-treatment. It could be important to take into consideration the dynamics of SWS when assessing their presence.
Original languageEnglish
Title of host publicationProceedings of the 62nd International Scientific Conference of Daugavpils University
Subtitle of host publicationPart A. Natural Sciences
EditorsIrēna Kokina
Place of PublicationDaugavpils
PublisherDaugavpils University
Pages139-143
ISBN (Print)978-9984-14-925-7
Publication statusPublished - 2020
EventDaugavpils Universitātes 62. starptautiskā zinātniskā konference = the 62nd International Scientific Conference of Daugavpils University - Daugavpils, Latvia
Duration: 28 May 202029 May 2020
Conference number: 62

Conference

ConferenceDaugavpils Universitātes 62. starptautiskā zinātniskā konference = the 62nd International Scientific Conference of Daugavpils University
CountryLatvia
CityDaugavpils
Period28/05/2029/05/20

Keywords

  • shiny white streaks
  • chrysalis structures
  • actinic keratosis
  • dermoscopy

Field of Science

  • 3.2 Clinical medicine

Publication Type

  • 3.2. Articles or chapters in other proceedings other than those included in 3.1., with an ISBN or ISSN code

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