Development of poly(vinyl alcohol) cryo-systems with medicines and their comparative study of antimicrobial activity and cytotoxicity

J. Stasko; N. Romanchikova; A. Reinis; L. Berzina-Cimdina; J. Kroica

doi:10.1007/978-3-642-34197-7_30

Development of poly(vinyl alcohol) cryo-systems with medicines and their comparative study of antimicrobial activity and cytotoxicity

J. Stasko, N. Romanchikova, A. Reinis, L. Berzina-Cimdina, J. Kroica

Department of Biology and Microbiology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

The aim of the work was to develop the poly(vinyl alcohol) cryogel systems (PVA_GS) with plant extracts (PPe) and simple conventional medicine (Cm), and compare their antimicrobial activity, biocompatibility and cytotoxicity. The stability of gels systems with and without medicines was determined, the gel content and swelling degree were calculated. In vitro studies of PVA_GS, with and without medicines, microbial contamination risk - the colonization level of the microorganisms and adhesion activity for the use of gel materials for the wound care were detected. PVA_GS biocompatibility and cytotoxic properties were examined on cell lines.

Original language	English
Title of host publication	International Symposium on Biomedical Engineering and Medical Physics, ISBEMP 2012
Editors	Yuri Dekhtyar, Alexei Katashev, Linda Lancere
Place of Publication	Riga
Pages	113-118
Number of pages	6
ISBN (Electronic)	978-3-642-34197-7
DOIs	https://doi.org/10.1007/978-3-642-34197-7_30
Publication status	Published - 2013
Event	International Symposium on Biomedical Engineering and Medical Physics - Riga, Latvia Duration: 10 Oct 2012 → 12 Oct 2012 https://link.springer.com/book/10.1007/978-3-642-34197-7 http://www.bini.rtu.lv/isbemp/

Publication series

Name	IFMBE Proceedings
Volume	38 IFMBE
ISSN (Print)	1680-0737

Symposium

Symposium	International Symposium on Biomedical Engineering and Medical Physics
Abbreviated title	ISBEMP 2012
Country/Territory	Latvia
City	Riga
Period	10/10/12 → 12/10/12
Internet address	https://link.springer.com/book/10.1007/978-3-642-34197-7 http://www.bini.rtu.lv/isbemp/

Keywords*

biocompatibility
cryogel systems
cytotoxicity
microbial adherence
poly(vinyl alcohol)

Field of Science*

2.6 Medical engineering
2.5 Materials engineering
3.1 Basic medicine

Publication Type*

3.3. Publications in conference proceedings indexed in Web of Science and/or Scopus database

Access to Document

10.1007/978-3-642-34197-7_30

Cite this

Stasko, J., Romanchikova, N., Reinis, A., Berzina-Cimdina, L., & Kroica, J. (2013). Development of poly(vinyl alcohol) cryo-systems with medicines and their comparative study of antimicrobial activity and cytotoxicity. In Y. Dekhtyar, A. Katashev, & L. Lancere (Eds.), International Symposium on Biomedical Engineering and Medical Physics, ISBEMP 2012 (pp. 113-118). (IFMBE Proceedings; Vol. 38 IFMBE).. https://doi.org/10.1007/978-3-642-34197-7_30

Stasko, J. ; Romanchikova, N. ; Reinis, A. et al. / Development of poly(vinyl alcohol) cryo-systems with medicines and their comparative study of antimicrobial activity and cytotoxicity. International Symposium on Biomedical Engineering and Medical Physics, ISBEMP 2012. editor / Yuri Dekhtyar ; Alexei Katashev ; Linda Lancere. Riga, 2013. pp. 113-118 (IFMBE Proceedings).

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title = "Development of poly(vinyl alcohol) cryo-systems with medicines and their comparative study of antimicrobial activity and cytotoxicity",

abstract = "The aim of the work was to develop the poly(vinyl alcohol) cryogel systems (PVAGS) with plant extracts (PPe) and simple conventional medicine (Cm), and compare their antimicrobial activity, biocompatibility and cytotoxicity. The stability of gels systems with and without medicines was determined, the gel content and swelling degree were calculated. In vitro studies of PVAGS, with and without medicines, microbial contamination risk - the colonization level of the microorganisms and adhesion activity for the use of gel materials for the wound care were detected. PVAGS biocompatibility and cytotoxic properties were examined on cell lines.",

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author = "J. Stasko and N. Romanchikova and A. Reinis and L. Berzina-Cimdina and J. Kroica",

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booktitle = "International Symposium on Biomedical Engineering and Medical Physics, ISBEMP 2012",

note = "International Symposium on Biomedical Engineering and Medical Physics, ISBEMP 2012 ; Conference date: 10-10-2012 Through 12-10-2012",

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Stasko, J, Romanchikova, N, Reinis, A, Berzina-Cimdina, L & Kroica, J 2013, Development of poly(vinyl alcohol) cryo-systems with medicines and their comparative study of antimicrobial activity and cytotoxicity. in Y Dekhtyar, A Katashev & L Lancere (eds), International Symposium on Biomedical Engineering and Medical Physics, ISBEMP 2012. IFMBE Proceedings, vol. 38 IFMBE, Riga, pp. 113-118, International Symposium on Biomedical Engineering and Medical Physics, Riga, Latvia, 10/10/12. https://doi.org/10.1007/978-3-642-34197-7_30

Development of poly(vinyl alcohol) cryo-systems with medicines and their comparative study of antimicrobial activity and cytotoxicity. / Stasko, J.; Romanchikova, N.; Reinis, A. et al.
International Symposium on Biomedical Engineering and Medical Physics, ISBEMP 2012. ed. / Yuri Dekhtyar; Alexei Katashev; Linda Lancere. Riga, 2013. p. 113-118 (IFMBE Proceedings; Vol. 38 IFMBE).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Kroica, J.

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AB - The aim of the work was to develop the poly(vinyl alcohol) cryogel systems (PVAGS) with plant extracts (PPe) and simple conventional medicine (Cm), and compare their antimicrobial activity, biocompatibility and cytotoxicity. The stability of gels systems with and without medicines was determined, the gel content and swelling degree were calculated. In vitro studies of PVAGS, with and without medicines, microbial contamination risk - the colonization level of the microorganisms and adhesion activity for the use of gel materials for the wound care were detected. PVAGS biocompatibility and cytotoxic properties were examined on cell lines.

KW - biocompatibility

KW - cryogel systems

KW - cytotoxicity

KW - microbial adherence

KW - poly(vinyl alcohol)

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BT - International Symposium on Biomedical Engineering and Medical Physics, ISBEMP 2012

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Stasko J, Romanchikova N, Reinis A, Berzina-Cimdina L, Kroica J. Development of poly(vinyl alcohol) cryo-systems with medicines and their comparative study of antimicrobial activity and cytotoxicity. In Dekhtyar Y, Katashev A, Lancere L, editors, International Symposium on Biomedical Engineering and Medical Physics, ISBEMP 2012. Riga. 2013. p. 113-118. (IFMBE Proceedings). doi: 10.1007/978-3-642-34197-7_30

Development of poly(vinyl alcohol) cryo-systems with medicines and their comparative study of antimicrobial activity and cytotoxicity

Abstract

Publication series

Symposium

Keywords*

Field of Science*

Publication Type*

Access to Document

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