Development of poly(vinyl alcohol) cryo-systems with medicines and their comparative study of antimicrobial activity and cytotoxicity

J. Stasko, N. Romanchikova, A. Reinis, L. Berzina-Cimdina, J. Kroica

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The aim of the work was to develop the poly(vinyl alcohol) cryogel systems (PVAGS) with plant extracts (PPe) and simple conventional medicine (Cm), and compare their antimicrobial activity, biocompatibility and cytotoxicity. The stability of gels systems with and without medicines was determined, the gel content and swelling degree were calculated. In vitro studies of PVAGS, with and without medicines, microbial contamination risk - the colonization level of the microorganisms and adhesion activity for the use of gel materials for the wound care were detected. PVAGS biocompatibility and cytotoxic properties were examined on cell lines.

Original languageEnglish
Title of host publicationInternational Symposium on Biomedical Engineering and Medical Physics, ISBEMP 2012
EditorsYuri Dekhtyar, Alexei Katashev, Linda Lancere
Place of PublicationRiga
Pages113-118
Number of pages6
ISBN (Electronic)978-3-642-34197-7
DOIs
Publication statusPublished - 2013
EventInternational Symposium on Biomedical Engineering and Medical Physics, ISBEMP 2012 - Riga, Latvia
Duration: 10 Oct 201212 Oct 2012

Publication series

NameIFMBE Proceedings
Volume38 IFMBE
ISSN (Print)1680-0737

Conference

ConferenceInternational Symposium on Biomedical Engineering and Medical Physics, ISBEMP 2012
Country/TerritoryLatvia
CityRiga
Period10/10/1212/10/12

Keywords*

  • biocompatibility
  • cryogel systems
  • cytotoxicity
  • microbial adherence
  • poly(vinyl alcohol)

Field of Science*

  • 2.6 Medical engineering
  • 2.5 Materials engineering
  • 3.1 Basic medicine

Publication Type*

  • 3.3. Publications in conference proceedings indexed in Web of Science and/or Scopus database

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