Dialysis and renal transplantation in HIV-infected patients: A European survey

Joan Carles Trullas; A. Mocroft; Federico Cofan; Jérome Tourret; Asunción Moreno; Corinne Isnard Bagnis; Christoph Andreas Fux; Christine Katlama; P. Reiss; Jens Lundgren; J. M. Gatell; Ole Kirk; J. M. Miró; EuroSIDA Investigators; Baiba Rozentāle; Indra Zeltiņa

doi:10.1097/QAI.0b013e3181efbe59

Dialysis and renal transplantation in HIV-infected patients: A European survey

Joan Carles Trullas
, A. Mocroft
, Federico Cofan
, Jérome Tourret
, Asunción Moreno
, Corinne Isnard Bagnis
, Christoph Andreas Fux
, Christine Katlama
, P. Reiss
, Jens Lundgren
, J. M. Gatell
, Ole Kirk
, J. M. Miró (Corresponding Author)
, EuroSIDA Investigators
, Baiba Rozentāle (Member of the Working Group)
, Indra Zeltiņa (Member of the Working Group)

Research output: Contribution to journal › Article › peer-review

50 Citations (Scopus)

Abstract

Objectives: To determine prevalence and characteristics of endstage renal diseases (ESRD) [dialysis and renal transplantation (RT)] among European HIV-infected patients. Methods: Cross-sectional multicenter survey of EuroSIDA clinics during 2008. Results: Prevalence of ESRD was 0.5%. Of 122 patients with ESRD 96 were on dialysis and 26 had received a RT.Median age was 47 years, 73%were males and 43% were black.Median duration of HIVinfection was 11 years. Thirty-three percent had prior AIDS; 91% were receiving antiretrovirals; and 88%had undetectable viral load. Median CD4+T-cell count was 341 cells per cubic millimetre; 20.5% had hepatitis C coinfection. Most frequent causes of ESRD were HIV-associated nephropathy (46%) and other glomerulonephritis (28%). Hemodialysis (93%) was the most common dialysis modality; 34% of patients were on the RT waiting list. A poor HIV control was the reason for exclusion from RT waiting list in 22.4% of cases. All the RT recipients were all alive at the time of the survey. Acute rejection was reported in 8 patients (30%). Functioning graft was present in 21 (80%). Conclusions: This is the first multinational cross-sectional study of ESRD among European HIV population. Low prevalence of ESRD was found. Two-thirds of patients were excluded from RT for non- HIV/AIDS-related pathologies. Most patients had a functioning graft despite a high acute rejection rate.

Original language	English
Pages (from-to)	582-589
Journal	Journal of Acquired Immune Deficiency Syndromes
Volume	55
Issue number	5
DOIs	https://doi.org/10.1097/QAI.0b013e3181efbe59
Publication status	Published - 15 Dec 2010
Externally published	Yes

Keywords*

chronic kidney failure
dialysis
HIV infection
kidney transplantation

Field of Science*

3.2 Clinical medicine
3.3 Health sciences

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1097/QAI.0b013e3181efbe59

Cite this

Trullas, J. C., Mocroft, A., Cofan, F., Tourret, J., Moreno, A., Bagnis, C. I., Fux, C. A., Katlama, C., Reiss, P., Lundgren, J., Gatell, J. M., Kirk, O., Miró, J. M., EuroSIDA Investigators, Rozentāle, B., & Zeltiņa, I. (2010). Dialysis and renal transplantation in HIV-infected patients: A European survey. Journal of Acquired Immune Deficiency Syndromes, 55(5), 582-589. https://doi.org/10.1097/QAI.0b013e3181efbe59

@article{e698562ec6c34199ab16b918f377c071,

title = "Dialysis and renal transplantation in HIV-infected patients: A European survey",

abstract = "Objectives: To determine prevalence and characteristics of endstage renal diseases (ESRD) [dialysis and renal transplantation (RT)] among European HIV-infected patients. Methods: Cross-sectional multicenter survey of EuroSIDA clinics during 2008. Results: Prevalence of ESRD was 0.5\%. Of 122 patients with ESRD 96 were on dialysis and 26 had received a RT.Median age was 47 years, 73\%were males and 43\% were black.Median duration of HIVinfection was 11 years. Thirty-three percent had prior AIDS; 91\% were receiving antiretrovirals; and 88\%had undetectable viral load. Median CD4+T-cell count was 341 cells per cubic millimetre; 20.5\% had hepatitis C coinfection. Most frequent causes of ESRD were HIV-associated nephropathy (46\%) and other glomerulonephritis (28\%). Hemodialysis (93\%) was the most common dialysis modality; 34\% of patients were on the RT waiting list. A poor HIV control was the reason for exclusion from RT waiting list in 22.4\% of cases. All the RT recipients were all alive at the time of the survey. Acute rejection was reported in 8 patients (30\%). Functioning graft was present in 21 (80\%). Conclusions: This is the first multinational cross-sectional study of ESRD among European HIV population. Low prevalence of ESRD was found. Two-thirds of patients were excluded from RT for non- HIV/AIDS-related pathologies. Most patients had a functioning graft despite a high acute rejection rate.",

keywords = "chronic kidney failure, dialysis, HIV infection, kidney transplantation",

author = "Trullas, \{Joan Carles\} and A. Mocroft and Federico Cofan and J{\'e}rome Tourret and Asunci{\'o}n Moreno and Bagnis, \{Corinne Isnard\} and Fux, \{Christoph Andreas\} and Christine Katlama and P. Reiss and Jens Lundgren and Gatell, \{J. M.\} and Ole Kirk and Mir{\'o}, \{J. M.\} and \{EuroSIDA Investigators\} and M. Losso and C. Elias and N. Vetter and R. Zangerle and I. Karpov and A. Vassilenko and Mitsura, \{V. M.\} and O. Suetnov and N. Clumeck and \{De Wit\}, S. and M. Delforge and R. Colebunders and L. Vandekerckhove and V. Hadziosmanovic and K. Kostov and J. Begovac and L. Machala and H. Rozsypal and D. Sedlacek and J. Nielsen and G. Kronborg and T. Benfield and M. Larsen and J. Gerstoft and T. Katzenstein and Hansen, \{A. B.E.\} and P. Skinh{\o}j and C. Pedersen and \{D Larsen\}, O. and L. Oestergaard and K. Zilmer and Jelena Smidt and M. Ristola and Viard, \{J. P.\} and Girard, \{P. M.\} and Livrozet, \{J. M.\} and P. Vanhems and C. Pradier and F. Dabis and D. Neau and J. Rockstroh and R. Schmidt and \{Van Lunzen\}, J. and O. Degen and Stellbrink, \{H. J.\} and S. Staszewski and J. Bogner and G. F{\"a}tkenheuer and J. Kosmidis and P. Gargalianos and G. Xylomenos and J. Perdios and A. Filandras and E. Karabatsaki and H. Sambatakou and D. Banhegyi and F. Mulcahy and I. Yust and D. Turner and M. Burke and S. Pollack and G. Hassoun and S. Maayan and A. Chiesi and R. Esposito and I. Mazeu and C. Mussini and C. Arici and R. Pristera and F. Mazzotta and A. Gabbuti and V. Vullo and M. Lichtner and A. Chirianni and E. Montesarchio and M. Gargiulo and G. Antonucci and F. Iacomi and P. Narciso and C. Vlassi and M. Zaccarelli and A. Lazzarin and R. Finazzi and M. Galli and A. Ridolfo and Monforte, \{A. D.Arminio\} and Baiba Rozentāle and Indra Zeltiņa",

note = "Publisher Copyright: Copyright {\textcopyright} 2010 by Lippincott Williams \& Wilkins.",

year = "2010",

month = dec,

day = "15",

doi = "10.1097/QAI.0b013e3181efbe59",

language = "English",

volume = "55",

pages = "582--589",

journal = "Journal of Acquired Immune Deficiency Syndromes",

issn = "1525-4135",

publisher = "Wolters Kluwer Health",

number = "5",

}

Trullas, JC, Mocroft, A, Cofan, F, Tourret, J, Moreno, A, Bagnis, CI, Fux, CA, Katlama, C, Reiss, P, Lundgren, J, Gatell, JM, Kirk, O, Miró, JM, EuroSIDA Investigators, Rozentāle, B & Zeltiņa, I 2010, 'Dialysis and renal transplantation in HIV-infected patients: A European survey', Journal of Acquired Immune Deficiency Syndromes, vol. 55, no. 5, pp. 582-589. https://doi.org/10.1097/QAI.0b013e3181efbe59

TY - JOUR

T1 - Dialysis and renal transplantation in HIV-infected patients

T2 - A European survey

AU - Trullas, Joan Carles

AU - Mocroft, A.

AU - Cofan, Federico

AU - Tourret, Jérome

AU - Moreno, Asunción

AU - Bagnis, Corinne Isnard

AU - Fux, Christoph Andreas

AU - Katlama, Christine

AU - Reiss, P.

AU - Lundgren, Jens

AU - Gatell, J. M.

AU - Kirk, Ole

AU - Miró, J. M.

AU - EuroSIDA Investigators

A2 - Losso, M.

A2 - Elias, C.

A2 - Vetter, N.

A2 - Zangerle, R.

A2 - Karpov, I.

A2 - Vassilenko, A.

A2 - Mitsura, V. M.

A2 - Suetnov, O.

A2 - Clumeck, N.

A2 - De Wit, S.

A2 - Delforge, M.

A2 - Colebunders, R.

A2 - Vandekerckhove, L.

A2 - Hadziosmanovic, V.

A2 - Kostov, K.

A2 - Begovac, J.

A2 - Machala, L.

A2 - Rozsypal, H.

A2 - Sedlacek, D.

A2 - Nielsen, J.

A2 - Kronborg, G.

A2 - Benfield, T.

A2 - Larsen, M.

A2 - Gerstoft, J.

A2 - Katzenstein, T.

A2 - Hansen, A. B.E.

A2 - Skinhøj, P.

A2 - Pedersen, C.

A2 - D Larsen, O.

A2 - Oestergaard, L.

A2 - Zilmer, K.

A2 - Smidt, Jelena

A2 - Ristola, M.

A2 - Viard, J. P.

A2 - Girard, P. M.

A2 - Livrozet, J. M.

A2 - Vanhems, P.

A2 - Pradier, C.

A2 - Dabis, F.

A2 - Neau, D.

A2 - Rockstroh, J.

A2 - Schmidt, R.

A2 - Van Lunzen, J.

A2 - Degen, O.

A2 - Stellbrink, H. J.

A2 - Staszewski, S.

A2 - Bogner, J.

A2 - Fätkenheuer, G.

A2 - Kosmidis, J.

A2 - Gargalianos, P.

A2 - Xylomenos, G.

A2 - Perdios, J.

A2 - Filandras, A.

A2 - Karabatsaki, E.

A2 - Sambatakou, H.

A2 - Banhegyi, D.

A2 - Mulcahy, F.

A2 - Yust, I.

A2 - Turner, D.

A2 - Burke, M.

A2 - Pollack, S.

A2 - Hassoun, G.

A2 - Maayan, S.

A2 - Chiesi, A.

A2 - Esposito, R.

A2 - Mazeu, I.

A2 - Mussini, C.

A2 - Arici, C.

A2 - Pristera, R.

A2 - Mazzotta, F.

A2 - Gabbuti, A.

A2 - Vullo, V.

A2 - Lichtner, M.

A2 - Chirianni, A.

A2 - Montesarchio, E.

A2 - Gargiulo, M.

A2 - Antonucci, G.

A2 - Iacomi, F.

A2 - Narciso, P.

A2 - Vlassi, C.

A2 - Zaccarelli, M.

A2 - Lazzarin, A.

A2 - Finazzi, R.

A2 - Galli, M.

A2 - Ridolfo, A.

A2 - Monforte, A. D.Arminio

A2 - Rozentāle, Baiba

A2 - Zeltiņa, Indra

PY - 2010/12/15

Y1 - 2010/12/15

N2 - Objectives: To determine prevalence and characteristics of endstage renal diseases (ESRD) [dialysis and renal transplantation (RT)] among European HIV-infected patients. Methods: Cross-sectional multicenter survey of EuroSIDA clinics during 2008. Results: Prevalence of ESRD was 0.5%. Of 122 patients with ESRD 96 were on dialysis and 26 had received a RT.Median age was 47 years, 73%were males and 43% were black.Median duration of HIVinfection was 11 years. Thirty-three percent had prior AIDS; 91% were receiving antiretrovirals; and 88%had undetectable viral load. Median CD4+T-cell count was 341 cells per cubic millimetre; 20.5% had hepatitis C coinfection. Most frequent causes of ESRD were HIV-associated nephropathy (46%) and other glomerulonephritis (28%). Hemodialysis (93%) was the most common dialysis modality; 34% of patients were on the RT waiting list. A poor HIV control was the reason for exclusion from RT waiting list in 22.4% of cases. All the RT recipients were all alive at the time of the survey. Acute rejection was reported in 8 patients (30%). Functioning graft was present in 21 (80%). Conclusions: This is the first multinational cross-sectional study of ESRD among European HIV population. Low prevalence of ESRD was found. Two-thirds of patients were excluded from RT for non- HIV/AIDS-related pathologies. Most patients had a functioning graft despite a high acute rejection rate.

AB - Objectives: To determine prevalence and characteristics of endstage renal diseases (ESRD) [dialysis and renal transplantation (RT)] among European HIV-infected patients. Methods: Cross-sectional multicenter survey of EuroSIDA clinics during 2008. Results: Prevalence of ESRD was 0.5%. Of 122 patients with ESRD 96 were on dialysis and 26 had received a RT.Median age was 47 years, 73%were males and 43% were black.Median duration of HIVinfection was 11 years. Thirty-three percent had prior AIDS; 91% were receiving antiretrovirals; and 88%had undetectable viral load. Median CD4+T-cell count was 341 cells per cubic millimetre; 20.5% had hepatitis C coinfection. Most frequent causes of ESRD were HIV-associated nephropathy (46%) and other glomerulonephritis (28%). Hemodialysis (93%) was the most common dialysis modality; 34% of patients were on the RT waiting list. A poor HIV control was the reason for exclusion from RT waiting list in 22.4% of cases. All the RT recipients were all alive at the time of the survey. Acute rejection was reported in 8 patients (30%). Functioning graft was present in 21 (80%). Conclusions: This is the first multinational cross-sectional study of ESRD among European HIV population. Low prevalence of ESRD was found. Two-thirds of patients were excluded from RT for non- HIV/AIDS-related pathologies. Most patients had a functioning graft despite a high acute rejection rate.

KW - chronic kidney failure

KW - dialysis

KW - HIV infection

KW - kidney transplantation

UR - https://www.scopus.com/pages/publications/78650202428

UR - https://pubmed.ncbi.nlm.nih.gov/20811290/

U2 - 10.1097/QAI.0b013e3181efbe59

DO - 10.1097/QAI.0b013e3181efbe59

M3 - Article

C2 - 20811290

AN - SCOPUS:78650202428

SN - 1525-4135

VL - 55

SP - 582

EP - 589

JO - Journal of Acquired Immune Deficiency Syndromes

JF - Journal of Acquired Immune Deficiency Syndromes

IS - 5

ER -

Dialysis and renal transplantation in HIV-infected patients: A European survey

Abstract

Keywords*

Field of Science*

Publication Type*

UN SDGs

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