Differences in weight, BMI and waist circumference reduction between clinically healthy overweight people with and without signs of fatty liver

Vija Siliņa (Coresponding Author), Mesfin K. Tessma, Gita Krievina, Pēteris Tretjakovs, Guntis Bahs

Research output: Contribution to conferenceAbstractpeer-review


Background: Motivatingclinically healthy overweight and obese individuals to bring lifestylebehavioural changes prior to an apparent disease is still a challenge.  There is evidence that fatty liver is relatedto cardiovascular diseases risks, however, it is not obvious that signs of fattyliver on a computed tomography (CT) scan, could be an argument to lose weightin behavioural consultations.

 Research question: Do people withsigns of fatty liver reduce weight, body mass index and waist circumferencemore effectively than those with no signs of fatty liver.

 Methods: A prospective observational studyin Riga, Latvia included 73 clinically healthy individuals having body massindex (BMI) above 25 m2/kg and below 40 m2/kg and in agegroup 30-45 that visited primary care physician. Individuals underwent CT scanfor signs of hepatic steatosis, as well as biochemical testing, and wereadvised to decrease weight and waist circumference by at least 5 % within ayear. We estimated weight and waist circumference differences between twogroups: those with signs of steatosis and without signs of steatosis.  A paired t test was employed to compare thewithin subject change and an independent t test to compare the means of the twogroups.

 Results: Study included 73 clinicallyhealthy individuals (age 37,2±4,4, BMI 31,6±3,7, including  25 men, age 37,1±4,3, BMI 31,7±3,3 and 48women, age 37,3±4,5, BMI 31,5±4,1) divided in two groups: those with signs ofsteatosis (age 36,2±4,5, weight 99,5±15,1 kg, BMI 32,6±4,3, waist 104,0±11,9cm) and without signs of steatosis (age 37,8±4,3, weight 88,5±11,3 kg, BMI31,1±3,6, waist 94,9±9,2 cm). We did not observe statistically significant between groupdifferences in weight or BMI reductions. A statistically significant pairedmean difference was observed in waist circumference reduction in individualswith steatosis signs (3,6 cm, 95% CI .69, 3.98; p=0,001) and without steatosis(2,3 cm, 95% CI 1.57, 5.75; p=0,006).

 Conclusions: For individualsresiding in Riga, Latvia presence of fatty liver signs is not a sufficientmotivation to reduce weight or waist circumference by at least 5% within a year,however, further researchis required with a larger sample size to examine the findings in this study  especially regarding waistcircumference reduction in both observed groups within a year.

Original languageEnglish
Number of pages1
Publication statusPublished - 2014
Event19th WONCA Europe Conference 2014: New Routes for General Practice and family Medicine - Lisbon, Portugal
Duration: 2 Jul 20145 Jul 2014
Conference number: 19


Conference19th WONCA Europe Conference 2014
Internet address


  • Overweight
  • Obesity

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 3.4. Other publications in conference proceedings (including local)


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