Abstract
Depending on the chemical structure peculiarities 1, 4-dihydropyridines possess electron/hydrogen donor, peptide type and lipid-like characteristics and many regulatory activities: neuro- and radio- protection, anti-mutagenic, antidiabetic, anti-inflammatory, anti-ischaemic/anti-anginal and anti-hypertensive actions, as well as growth stimulating and gene transaction properties. These effects appear mostly in low concentrations/doses and show a long-term manifestation. Green chemistry approaches and chemoenzymatic transformations have been used for synthesis of novel bioprotective compounds. This mini-review comprises mainly the data obtained at the Latvian Institute of Organic Synthesis.
Original language | English |
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Pages (from-to) | 68-70 |
Number of pages | 3 |
Journal | Chimica Oggi |
Volume | 26 |
Issue number | 2 |
Publication status | Published - Mar 2008 |
Externally published | Yes |
Field of Science*
- 1.4 Chemical sciences
Publication Type*
- 1.1. Scientific article indexed in Web of Science and/or Scopus database