Donation after circulatory death today: an updated overview of the European landscape

Mar Lomero; Dale Gardiner; Elisabeth Coll; Bernadette Haase-Kromwijk; Francesco Procaccio; Franz Immer; Lyalya Gabbasova; Corine Antoine; Janis Jushinskis; Nessa Lynch; Stein Foss; Catarina Bolotinha; Tamar Ashkenazi; Luc Colenbie; Andreas Zuckermann; Miloš Adamec; Jarosław Czerwiński; Sonata Karčiauskaitė; Helena Ström; Marta López-Fraga; Beatriz Dominguez-Gil; the European Committee on Organ Transplantation of the Council of Europe (CD-P-TO)

doi:10.1111/tri.13506

Donation after circulatory death today: an updated overview of the European landscape

Mar Lomero, Dale Gardiner, Elisabeth Coll, Bernadette Haase-Kromwijk, Francesco Procaccio, Franz Immer, Lyalya Gabbasova, Corine Antoine, Janis Jushinskis, Nessa Lynch, Stein Foss, Catarina Bolotinha, Tamar Ashkenazi, Luc Colenbie, Andreas Zuckermann, Miloš Adamec, Jarosław Czerwiński, Sonata Karčiauskaitė, Helena Ström, Marta López-FragaBeatriz Dominguez-Gil (Corresponding Author), the European Committee on Organ Transplantation of the Council of Europe (CD-P-TO)

Research output: Contribution to journal › Article › peer-review

203 Citations (Scopus)

Abstract

Donation after circulatory death (DCD) has become an accepted practice in many countries and remains a focus of intense interest in the transplant community. The present study is aimed at providing a description of the current situation of DCD in European countries. Specific questionnaires were developed to compile information on DCD practices, activities and post-transplant outcomes. Thirty-five countries completed the survey. DCD is practiced in 18 countries: eight have both controlled DCD (cDCD) and uncontrolled DCD (uDCD) programs, 4 only cDCD and 6 only uDCD. All these countries have legally binding and/or nonbinding texts to regulate the practice of DCD. The no-touch period ranges from 5 to 30 min. There are variations in ante and post mortem interventions used for the practice of cDCD. During 2008–2016, the highest DCD activity was described in the United Kingdom, Spain, Russia, the Netherlands, Belgium and France. Data on post-transplant outcomes of patients who receive DCD donor kidneys show better results with grafts obtained from cDCD versus uDCD donors. In conclusion, DCD is becoming increasingly accepted and performed in Europe, importantly contributing to the number of organs available and providing acceptable post-transplantation outcomes.

Original language	English
Pages (from-to)	76-88
Number of pages	13
Journal	Transplant International
Volume	33
Issue number	1
DOIs	https://doi.org/10.1111/tri.13506
Publication status	Published - 1 Jan 2020
Externally published	Yes

Keywords*

brain death
donation after circulatory death
normothermic regional perfusion
organ donation
transplantation

Field of Science*

3.2 Clinical medicine

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

Access to Document

10.1111/tri.13506

Cite this

Lomero, M., Gardiner, D., Coll, E., Haase-Kromwijk, B., Procaccio, F., Immer, F., Gabbasova, L., Antoine, C., Jushinskis, J., Lynch, N., Foss, S., Bolotinha, C., Ashkenazi, T., Colenbie, L., Zuckermann, A., Adamec, M., Czerwiński, J., Karčiauskaitė, S., Ström, H., ... the European Committee on Organ Transplantation of the Council of Europe (CD-P-TO) (2020). Donation after circulatory death today: an updated overview of the European landscape. Transplant International, 33(1), 76-88. https://doi.org/10.1111/tri.13506

@article{310395bac5f64e5a9019840e7719e7a2,

title = "Donation after circulatory death today: an updated overview of the European landscape",

abstract = "Donation after circulatory death (DCD) has become an accepted practice in many countries and remains a focus of intense interest in the transplant community. The present study is aimed at providing a description of the current situation of DCD in European countries. Specific questionnaires were developed to compile information on DCD practices, activities and post-transplant outcomes. Thirty-five countries completed the survey. DCD is practiced in 18 countries: eight have both controlled DCD (cDCD) and uncontrolled DCD (uDCD) programs, 4 only cDCD and 6 only uDCD. All these countries have legally binding and/or nonbinding texts to regulate the practice of DCD. The no-touch period ranges from 5 to 30 min. There are variations in ante and post mortem interventions used for the practice of cDCD. During 2008–2016, the highest DCD activity was described in the United Kingdom, Spain, Russia, the Netherlands, Belgium and France. Data on post-transplant outcomes of patients who receive DCD donor kidneys show better results with grafts obtained from cDCD versus uDCD donors. In conclusion, DCD is becoming increasingly accepted and performed in Europe, importantly contributing to the number of organs available and providing acceptable post-transplantation outcomes.",

keywords = "brain death, donation after circulatory death, normothermic regional perfusion, organ donation, transplantation",

author = "Mar Lomero and Dale Gardiner and Elisabeth Coll and Bernadette Haase-Kromwijk and Francesco Procaccio and Franz Immer and Lyalya Gabbasova and Corine Antoine and Janis Jushinskis and Nessa Lynch and Stein Foss and Catarina Bolotinha and Tamar Ashkenazi and Luc Colenbie and Andreas Zuckermann and Milo{\v s} Adamec and Jaros{\l}aw Czerwi{\'n}ski and Sonata Kar{\v c}iauskaitė and Helena Str{\"o}m and Marta L{\'o}pez-Fraga and Beatriz Dominguez-Gil and {the European Committee on Organ Transplantation of the Council of Europe (CD-P-TO)} and Ashot Sarkissian and Siarhei Liashchuk and Evelina Tsvetkova and Mirela Bu{\v s}i{\'c} and Nicolaos Michael and Ilkjaer, {Lars Bo} and Peeter Dmitriev and Heikki Makisalo and Axel Rahmel and Gia Tomadze and Boletis Ioannis and S{\'a}ndor Mih{\'a}ly and Claudia Carella and Igor Codreanu and Nichon Jansen and Cynthia Konijn and Ana Fran{\c c}a and Victor Zota and Zuzana {\v Z}ilinsk{\'a} and Danica Avsec and Sergey Gautier and Jacinto S{\'a}nchez-Ib{\'a}{\~n}ez and Christel Terr{\'o}n and Cristina Vidal and Franziska Beyeler and Julius Weiss and Tuna Ilbars and John Forsythe and Rachel Johnson",

note = "{\textcopyright} 2019 Steunstichting ESOT.",

year = "2020",

month = jan,

day = "1",

doi = "10.1111/tri.13506",

language = "English",

volume = "33",

pages = "76--88",

journal = "Transplant International",

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Lomero, M, Gardiner, D, Coll, E, Haase-Kromwijk, B, Procaccio, F, Immer, F, Gabbasova, L, Antoine, C, Jushinskis, J, Lynch, N, Foss, S, Bolotinha, C, Ashkenazi, T, Colenbie, L, Zuckermann, A, Adamec, M, Czerwiński, J, Karčiauskaitė, S, Ström, H, López-Fraga, M, Dominguez-Gil, B & the European Committee on Organ Transplantation of the Council of Europe (CD-P-TO) 2020, 'Donation after circulatory death today: an updated overview of the European landscape', Transplant International, vol. 33, no. 1, pp. 76-88. https://doi.org/10.1111/tri.13506

TY - JOUR

T1 - Donation after circulatory death today

T2 - an updated overview of the European landscape

AU - Lomero, Mar

AU - Gardiner, Dale

AU - Coll, Elisabeth

AU - Haase-Kromwijk, Bernadette

AU - Procaccio, Francesco

AU - Immer, Franz

AU - Gabbasova, Lyalya

AU - Antoine, Corine

AU - Jushinskis, Janis

AU - Lynch, Nessa

AU - Foss, Stein

AU - Bolotinha, Catarina

AU - Ashkenazi, Tamar

AU - Colenbie, Luc

AU - Zuckermann, Andreas

AU - Adamec, Miloš

AU - Czerwiński, Jarosław

AU - Karčiauskaitė, Sonata

AU - Ström, Helena

AU - López-Fraga, Marta

AU - Dominguez-Gil, Beatriz

AU - the European Committee on Organ Transplantation of the Council of Europe (CD-P-TO)

A2 - Sarkissian, Ashot

A2 - Liashchuk, Siarhei

A2 - Tsvetkova, Evelina

A2 - Bušić, Mirela

A2 - Michael, Nicolaos

A2 - Ilkjaer, Lars Bo

A2 - Dmitriev, Peeter

A2 - Makisalo, Heikki

A2 - Rahmel, Axel

A2 - Tomadze, Gia

A2 - Ioannis, Boletis

A2 - Mihály, Sándor

A2 - Carella, Claudia

A2 - Codreanu, Igor

A2 - Jansen, Nichon

A2 - Konijn, Cynthia

A2 - França, Ana

A2 - Zota, Victor

A2 - Žilinská, Zuzana

A2 - Avsec, Danica

A2 - Gautier, Sergey

A2 - Sánchez-Ibáñez, Jacinto

A2 - Terrón, Christel

A2 - Vidal, Cristina

A2 - Beyeler, Franziska

A2 - Weiss, Julius

A2 - Ilbars, Tuna

A2 - Forsythe, John

A2 - Johnson, Rachel

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Donation after circulatory death (DCD) has become an accepted practice in many countries and remains a focus of intense interest in the transplant community. The present study is aimed at providing a description of the current situation of DCD in European countries. Specific questionnaires were developed to compile information on DCD practices, activities and post-transplant outcomes. Thirty-five countries completed the survey. DCD is practiced in 18 countries: eight have both controlled DCD (cDCD) and uncontrolled DCD (uDCD) programs, 4 only cDCD and 6 only uDCD. All these countries have legally binding and/or nonbinding texts to regulate the practice of DCD. The no-touch period ranges from 5 to 30 min. There are variations in ante and post mortem interventions used for the practice of cDCD. During 2008–2016, the highest DCD activity was described in the United Kingdom, Spain, Russia, the Netherlands, Belgium and France. Data on post-transplant outcomes of patients who receive DCD donor kidneys show better results with grafts obtained from cDCD versus uDCD donors. In conclusion, DCD is becoming increasingly accepted and performed in Europe, importantly contributing to the number of organs available and providing acceptable post-transplantation outcomes.

AB - Donation after circulatory death (DCD) has become an accepted practice in many countries and remains a focus of intense interest in the transplant community. The present study is aimed at providing a description of the current situation of DCD in European countries. Specific questionnaires were developed to compile information on DCD practices, activities and post-transplant outcomes. Thirty-five countries completed the survey. DCD is practiced in 18 countries: eight have both controlled DCD (cDCD) and uncontrolled DCD (uDCD) programs, 4 only cDCD and 6 only uDCD. All these countries have legally binding and/or nonbinding texts to regulate the practice of DCD. The no-touch period ranges from 5 to 30 min. There are variations in ante and post mortem interventions used for the practice of cDCD. During 2008–2016, the highest DCD activity was described in the United Kingdom, Spain, Russia, the Netherlands, Belgium and France. Data on post-transplant outcomes of patients who receive DCD donor kidneys show better results with grafts obtained from cDCD versus uDCD donors. In conclusion, DCD is becoming increasingly accepted and performed in Europe, importantly contributing to the number of organs available and providing acceptable post-transplantation outcomes.

KW - brain death

KW - donation after circulatory death

KW - normothermic regional perfusion

KW - organ donation

KW - transplantation

UR - http://www.scopus.com/inward/record.url?scp=85071996198&partnerID=8YFLogxK

U2 - 10.1111/tri.13506

DO - 10.1111/tri.13506

M3 - Article

C2 - 31482628

AN - SCOPUS:85071996198

SN - 0934-0874

VL - 33

SP - 76

EP - 88

JO - Transplant International

JF - Transplant International

IS - 1

ER -

Donation after circulatory death today: an updated overview of the European landscape

Abstract

Keywords*

Field of Science*

Publication Type*

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