Effect of different types of intermittent fasting on biochemical and anthropometric parameters among patients with metabolic-associated fatty liver disease (MAFLD)—A systematic review

Gracjan Różański, Derek Pheby, Julia L. Newton, Modra Murovska, Paweł Zalewski, Joanna Słomko

Research output: Contribution to journalReview articlepeer-review

Abstract

Metabolic-associated fatty liver disease (MAFLD), previously called non-alcoholic fatty liver disease (NAFLD), is the most common chronic liver disease worldwide. It is characterised by excessive fat accumulation in hepatocytes. Currently, no pharmacological therapy is effective for this disease, so non-pharmacological alternatives such as diet, supplementation or physical activity are being sought. For this reason, we reviewed the available databases to analyse the studies con-ducted to date using different modifications of intermittent fasting among patients with MAFLD. Eight studies using this dietary strategy were included in this review. The results obtained in the different trials are varied and do not allow a clear determination of the effect of the different types of intermittent fasting on anthropometric and biochemical parameters among patients with MAFLD. However, this type of diet seems to show some therapeutic potential, but further studies are needed.

Original languageEnglish
Article number91
JournalNutrients
Volume14
Issue number1
DOIs
Publication statusPublished - 1 Jan 2022

Keywords*

  • Diet
  • Intermittent fasting
  • Liver
  • MAFLD

Field of Science*

  • 3.1 Basic medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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