Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt

Valentyn Mohylyuk; Kirils Kukuls; Alīna Jaroslava Frolova; Zoltan Mark Horvath; Elzbieta Maria Buczkowska; Līga Pētersone

doi:10.13140/RG.2.2.20606.70726

Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt

Valentyn Mohylyuk (Corresponding Author)
, Kirils Kukuls
, Alīna Jaroslava Frolova
, Zoltan Mark Horvath
, Elzbieta Maria Buczkowska
, Līga Pētersone

Lead Researcher Group

Research output: Contribution to conference › Poster

5 Downloads (Pure)

Original language	English
Pages	M034
DOIs	https://doi.org/10.13140/RG.2.2.20606.70726
Publication status	Published - 24 Mar 2025
Event	5th European Conference on Pharmaceutics - Alfandega Congress Center (EDIFÍCIO DA ALFÂNDEGA, R. Nova da Alfândega), Porto, Portugal Duration: 24 Mar 2025 → 25 Mar 2025 Conference number: 5 https://www.europeanmeeting.org/index.html

Conference

Conference	5th European Conference on Pharmaceutics
Abbreviated title	ECP
Country/Territory	Portugal
City	Porto
Period	24/03/25 → 25/03/25
Internet address	https://www.europeanmeeting.org/index.html

Keywords*

tableting
polyols
isomalt
mannitol
direct compression
Particle size distribution
pXRD
densification
microscopy
tablet hardness

Field of Science*

1.4 Chemical sciences
2.4 Chemical engineering
2.5 Materials engineering
3.1 Basic medicine

Publication Type*

3.4. Other publications in conference proceedings (including local)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.13140/RG.2.2.20606.70726Licence: CC BY

Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of IsomaltFinal published version, 1.38 MB

Cite this

Mohylyuk, V., Kukuls, K., Frolova, A. J., Horvath, Z. M., Buczkowska, E. M., & Pētersone, L. (2025). Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt. M034 . Poster session presented at 5th European Conference on Pharmaceutics, Porto, Portugal. https://doi.org/10.13140/RG.2.2.20606.70726

@conference{ae39a0dc20b34f888a52b96c71ea2deb,

title = "Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt",

keywords = "tableting, polyols, isomalt, mannitol, direct compression, Particle size distribution, pXRD, densification, microscopy, tablet hardness",

author = "Valentyn Mohylyuk and Kirils Kukuls and Frolova, \{Alīna Jaroslava\} and Horvath, \{Zoltan Mark\} and Buczkowska, \{Elzbieta Maria\} and Līga Pētersone",

year = "2025",

month = mar,

day = "24",

doi = "10.13140/RG.2.2.20606.70726",

language = "English",

pages = "M034 ",

note = "5th European Conference on Pharmaceutics, ECP ; Conference date: 24-03-2025 Through 25-03-2025",

url = "https://www.europeanmeeting.org/index.html",

}

Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt. / Mohylyuk, Valentyn (Corresponding Author); Kukuls, Kirils ; Frolova, Alīna Jaroslava et al.
2025. M034 Poster session presented at 5th European Conference on Pharmaceutics, Porto, Portugal.

Research output: Contribution to conference › Poster

TY - CONF

T1 - Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt

AU - Mohylyuk, Valentyn

AU - Kukuls, Kirils

AU - Frolova, Alīna Jaroslava

AU - Horvath, Zoltan Mark

AU - Buczkowska, Elzbieta Maria

AU - Pētersone, Līga

N1 - Conference code: 5

PY - 2025/3/24

Y1 - 2025/3/24

KW - tableting

KW - polyols

KW - isomalt

KW - mannitol

KW - direct compression

KW - Particle size distribution

KW - pXRD

KW - densification

KW - microscopy

KW - tablet hardness

UR - https://www.linkedin.com/feed/update/urn:li:activity:7308025562990546944

U2 - 10.13140/RG.2.2.20606.70726

DO - 10.13140/RG.2.2.20606.70726

M3 - Poster

SP - M034

T2 - 5th European Conference on Pharmaceutics

Y2 - 24 March 2025 through 25 March 2025

ER -

Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt

Conference

Keywords*

Field of Science*

Publication Type*

UN SDGs

Access to Document

Other files and links

Difference in Tableting of Lubricated Spray-Dried Mannitol and Fluid-Bed Granulated Isomalt

Effervescent Tablet Preparation by Twin-Screw Melt Granulation with Sorbitol as a Melt Binder

Isomalt as PVP-Binder Replacement in High-Shear Wet Granulation for Tablet Preparation

Suitability of sugar alcohols (polyols) as binders in twin-screw melt granulation for preparation of high-drug-loaded immediate-release tablets with superior mechanical properties

Optical Microscopy of Polyols

Loss on Drying (LoD) of Polyols

Densification Profiles of Polyols

Journal of Pharmaceutical Innovation (Journal)

Oliver Luhn

Journal of Drug Delivery Science and Technology (Journal)

Cite this

Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt

Conference

Keywords*

Field of Science*

Publication Type*

UN SDGs

Access to Document

Other files and links

Research output

Projects

Datasets

Activities

Cite this