Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt

Valentyn Mohylyuk; Kirils Kukuls; Alīna Jaroslava Frolova; Zoltan Mark Horvath; Elzbieta Maria Buczkowska; Līga Pētersone

doi:10.13140/RG.2.2.20606.70726

Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt

Valentyn Mohylyuk (Corresponding Author)
, Kirils Kukuls
, Alīna Jaroslava Frolova
, Zoltan Mark Horvath
, Elzbieta Maria Buczkowska
, Līga Pētersone

Lead Researcher Group

Research output: Contribution to conference › Poster

7 Downloads (Pure)

Original language	English
Pages	M034
DOIs	https://doi.org/10.13140/RG.2.2.20606.70726
Publication status	Published - 24 Mar 2025
Event	5th European Conference on Pharmaceutics - Alfandega Congress Center (EDIFÍCIO DA ALFÂNDEGA, R. Nova da Alfândega), Porto, Portugal Duration: 24 Mar 2025 → 25 Mar 2025 Conference number: 5 https://www.europeanmeeting.org/index.html

Conference

Conference	5th European Conference on Pharmaceutics
Abbreviated title	ECP
Country/Territory	Portugal
City	Porto
Period	24/03/25 → 25/03/25
Internet address	https://www.europeanmeeting.org/index.html

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 9 Industry, Innovation, and Infrastructure

Keywords*

tableting
polyols
isomalt
mannitol
direct compression
Particle size distribution
pXRD
densification
microscopy
tablet hardness

Field of Science*

2.5 Materials engineering
3.1 Basic medicine
1.4 Chemical sciences
2.4 Chemical engineering

Publication Type*

3.4. Other publications in conference proceedings (including local)

Access to Document

10.13140/RG.2.2.20606.70726Licence: CC BY

Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of IsomaltFinal published version, 1.38 MB

Cite this

Mohylyuk, V., Kukuls, K., Frolova, A. J., Horvath, Z. M., Buczkowska, E. M., & Pētersone, L. (2025). Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt. M034 . Poster session presented at 5th European Conference on Pharmaceutics, Porto, Portugal. https://doi.org/10.13140/RG.2.2.20606.70726

@conference{ae39a0dc20b34f888a52b96c71ea2deb,

title = "Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt",

keywords = "tableting, polyols, isomalt, mannitol, direct compression, Particle size distribution, pXRD, densification, microscopy, tablet hardness",

author = "Valentyn Mohylyuk and Kirils Kukuls and Frolova, \{Alīna Jaroslava\} and Horvath, \{Zoltan Mark\} and Buczkowska, \{Elzbieta Maria\} and Līga Pētersone",

year = "2025",

month = mar,

day = "24",

doi = "10.13140/RG.2.2.20606.70726",

language = "English",

pages = "M034 ",

note = "5th European Conference on Pharmaceutics, ECP ; Conference date: 24-03-2025 Through 25-03-2025",

url = "https://www.europeanmeeting.org/index.html",

}

Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt. / Mohylyuk, Valentyn (Corresponding Author); Kukuls, Kirils; Frolova, Alīna Jaroslava et al.
2025. M034 Poster session presented at 5th European Conference on Pharmaceutics, Porto, Portugal.

Research output: Contribution to conference › Poster

TY - CONF

T1 - Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt

AU - Mohylyuk, Valentyn

AU - Kukuls, Kirils

AU - Frolova, Alīna Jaroslava

AU - Horvath, Zoltan Mark

AU - Buczkowska, Elzbieta Maria

AU - Pētersone, Līga

N1 - Conference code: 5

PY - 2025/3/24

Y1 - 2025/3/24

KW - tableting

KW - polyols

KW - isomalt

KW - mannitol

KW - direct compression

KW - Particle size distribution

KW - pXRD

KW - densification

KW - microscopy

KW - tablet hardness

UR - https://www.linkedin.com/feed/update/urn:li:activity:7308025562990546944

U2 - 10.13140/RG.2.2.20606.70726

DO - 10.13140/RG.2.2.20606.70726

M3 - Poster

SP - M034

T2 - 5th European Conference on Pharmaceutics

Y2 - 24 March 2025 through 25 March 2025

ER -

Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt

Conference

UN SDGs

Keywords*

Field of Science*

Publication Type*

Access to Document

Other files and links

Difference in Tableting of Lubricated Spray-Dried Mannitol and Fluid-Bed Granulated Isomalt

Effervescent Tablet Preparation by Twin-Screw Melt Granulation with Sorbitol as a Melt Binder

Isomalt as PVP-Binder Replacement in High-Shear Wet Granulation for Tablet Preparation

Suitability of sugar alcohols (polyols) as binders in twin-screw melt granulation for preparation of high-drug-loaded immediate-release tablets with superior mechanical properties

Optical Microscopy of Polyols

Loss on Drying (LoD) of Polyols

Densification Profiles of Polyols

Oliver Luhn

Isomalt as PVP-Binder Replacement in High-Shear Wet Granulation for Tablet Preparation

Effect of Magnesium Stearate Amount on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt

Cite this

Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and Fluid-Bed Granulated Grade of Isomalt

Conference

UN SDGs

Keywords*

Field of Science*

Publication Type*

Access to Document

Other files and links

Research output

Projects

Datasets

Activities

Cite this