The pharmaceutical industry has a growing interest in continuous manufacturing, particularly for high-volume dosage forms such as solid oral tablets. This is driven by the obvious benefits such as small footprint, batch size flexibility, the relative simplicity of scale-up and process control. Tablets are the most popular solid dosage form, while batch granulation is one of the most often used technologies in tablet manufacturing. Using ascorbic acid as a model, we show the possibility of producing granules and tablets with a sustained-release profile using three technological operations: mixing, continuous melt-granulation, and tableting.
|Journal||British Journal of Pharmacy|
|Publication status||Published - 2022|
|Event||13th Conference of Academy of Pharmaceutical Sciences (APS) - PharmSci International Conference 2022 - Belfast, United Kingdom|
Duration: 7 Sept 2022 → 9 Sept 2022
Field of Science*
- 3.1 Basic medicine
- 1.4. Reviewed scientific article published in Latvia or abroad in a scientific journal with an editorial board (including university editions)