Effect on drying conditions on amorphous calcium phosphate

Agnese Brangule, Karlis Agris Gross

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Citations (Scopus)

Abstract

Amorphous calcium phosphate (ACP) plays an important role in the body and can be used as an intermediate phase for forming calcium phosphates. All ACPs are thermodynamically unstable compounds unless stored in dry conditions and spontaneously undergo transformation to crystalline calcium phosphates (CaP). This work will investigate the influence of drying on the stability of ACP. ACP powders were prepared by wet synthesis where a calcium containing solution was rapidly mixed with a phosphate solution. The suspension was stirred, filtered and washed and the filter cake was dried at different conditions and with different drying agents. XRD patterns and FTIR spectra showed low crystallinity powders after drying. FTIR spectra suggested residual organic groups after drying with ethanol. The Rietveld's method and Scherrer's relationship estimated the crystallite size as about 15-20 nm. Thermogravimetry (TG) revealed a 7-25% weight loss upon drying. The drying agents have limited effect on particle characteristics. By changing the drying conditions, it is a possible to retain the amorphous calcium phosphate or adjust the particle size, level of crystallinity, moisture content and type of carbonate modification in the apatite lattice.

Original languageEnglish
Title of host publicationBioceramics 26
EditorsMaria-Pau Ginebra, Cristina Canal, Montserrat Espanol, Edgar B. Montufar, Roman A. Perez
PublisherTrans Tech Publications Ltd
Pages99-103
Number of pages5
ISBN (Electronic)9783038352822
DOIs
Publication statusPublished - 2015
Event26th Symposium and Annual Meeting of the International Society for Ceramics in Medicine - Barcelona, Spain
Duration: 6 Nov 20148 Nov 2014
Conference number: 26

Publication series

NameKey Engineering Materials
Volume631
ISSN (Print)1013-9826
ISSN (Electronic)1662-9795

Conference

Conference26th Symposium and Annual Meeting of the International Society for Ceramics in Medicine
Abbreviated titleISCM 2014
Country/TerritorySpain
CityBarcelona
Period6/11/148/11/14

Keywords

  • Amorphous calcium phosphate
  • Drying agents
  • Drying conditions
  • FTIR DRIFT
  • XRD

Field of Science

  • 2.5 Materials engineering
  • 2.3 Mechanical engineering
  • 1.6 Biological sciences

Publication Type

  • 3.1. Articles or chapters in proceedings/scientific books indexed in Web of Science and/or Scopus database

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