Effectiveness of the autumn 2023 COVID-19 vaccine dose in hospital-based healthcare workers: results of the VEBIS healthcare worker vaccine effectiveness cohort study, seven European countries, season 2023/24

Camelia Savulescu (Corresponding Author), Kim Brolin, Albert Prats-Uribe, Dace Zavadska, Dagne Gravele, VEBIS HCW VE study group

Research output: Contribution to journalArticlepeer-review

Abstract

COVID-19 vaccination recommendations include healthcare workers (HCWs). We measured COVID-19 vaccine effectiveness (CVE) of the autumn 2023 dose against laboratory-confirmed SARS-CoV-2 infection in a prospective cohort study of 1,305 HCWs from 13 European hospitals. Overall CVE was 22% (95% CI: -17 to 48), 49% (95% CI: -8 to 76) before and -11% (95% CI: -84 to 34) after the start of BA.2.86/JN.1 predominant circulation. Autumn 2023 COVID-19 vaccination led to a moderate-to-low reduction in SARS-CoV-2 infection incidence in HCWs. Monitoring of CVE is crucial for COVID-19 prevention.

Original languageEnglish
Pages (from-to)1-8
JournalEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Volume29
Issue number44
DOIs
Publication statusPublished - 1 Oct 2024
Externally publishedYes

Keywords*

  • COVID-19
  • Europe
  • Healthcare workers
  • SARS-CoV-2
  • Vaccine effectiveness

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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