Effects of optical radiation on the healing of bone defect in rabbits

Yu Dehktyar, Alexei Katashev, J. Katasheva, I. Ozolanta

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Hypothesis, that optical radiation is able to alter surface electrochemical potential and due to this affect bone remodeling processes have been proposed. Besides, researches, being done beforehand, in majority used laser radiation of single wavelength; the latter usually does not match well with optical absorption bands of the bone, obtained in a series of in-vitro experiments. The goal of the present work was to evaluate in-vivo influence of the optical light of different wavelength on the bone remodeling / reconstruction process. For this, artificial defect have been made at the mandible bone of female rabbits. During operation and 10 days after surgery operation site was irradiated with optical radiation with either long (550 - 5000 nm) or short (350 - 550) wavelength. Results demonstrated that light treatment suppresses rate of healing of the bone defect for both experimental groups comparing with the control. The suppression effect is more expressed for short-wavelength irradiation.

Original languageEnglish
Title of host publication14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2008
PublisherSpringer Verlag
Pages357-360
Number of pages4
ISBN (Print)9783540693666
DOIs
Publication statusPublished - 2008

Publication series

NameIFMBE Proceedings
Volume20 IFMBE
ISSN (Print)1680-0737

Keywords*

  • bone remodeling
  • fracture healing
  • optical radiation

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 3.1. Articles or chapters in proceedings/scientific books indexed in Web of Science and/or Scopus database

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