Evaluation of risk factors for perioperative complications after radical cystectomy

Igors Andžāns, Māris Jakubovskis, Sergejs Beketovs, Jānis Auziņš, Kļims Ļeoņenko (Coresponding Author), Diāna Andžāne, Vilnis Lietuvietis

Research output: Contribution to conferenceAbstractpeer-review

Abstract

Older age and comorbidities are associated with increased perioperative risks and mortality. The mean age of the patients who underwent radical cystectomy (RC) continues to increase. The aim of study was to evaluate the relationship between the rate of perioperative complications, age and comorbidities in patients who undergo RC. A retrospective analysis of 144 patients who underwent RC due to muscle-invasive bladder cancer between January 1st, 2016 and December 31st, 2019 in Riga East University Hospital, Urology and Urologic Oncology Center was performed. The comorbidities of the patients were assessed according to American Society of Anesthesiology (ASA) classification and Charlson Comorbidity Index (CCI). 125 (86,8%) males and 19 (13,2%) females were included in the study. The mean age was 67,9 ± 8,7 (35-86) years, median age - 69,0 years. Intrahospital mortality (30-day mortality) was 6,9%(10 patients) and 90-day mortality was 12,5%(18 patients). Postoperative complications were observed in 84(58,3%) cases. Comparing age groups >75 years and <75 years there was 4-fold increase in intrahospital mortality (6 patients(15%) vs. 4(3,8%), p=0,018) and 3-fold increase in 90-day mortality (10 patients(25%) vs. 8(7,7%), p=0,009) in age group >75 years. There was 10-fold (7 patients(25,0%) vs. 3(2,6%), p=0,000) and 5-fold (10 patients(35,7%) vs. 8(6,9%), p=0,000) increase in intrahospital and 90-day mortality accordingly in patients with CCI<50% compared to patients with CCI>50%. Comparing groups by the ASA score there was 3-fold increase in intrahospital mortality (10 patients(10,9%) vs. 0(0%), p=0,014) and 5-fold increase in 90-day mortality (16 patients(17,4%) vs. 2(3,8%), p=0,019) in the group ASA≥3. In the group CCI<50% there was approximately 1,5-fold increase in the rate of intraoperative complications compared to group CCI>50% (23 patients(82,1%) vs. 61(52,6%), p=0,005). Increased patient’s age, ASA score un CCI is associated with increased complication rate and mortality. Summary comorbidity measures should be used in patient selection for surgery.
Original languageEnglish
Pages92
Publication statusPublished - 24 Mar 2021
EventRSU Research week 2021: Knowledge for Use in Practice - Rīga, Latvia
Duration: 24 Mar 202126 Mar 2021
https://rw2021.rsu.lv/conferences/knowledge-use-practice

Conference

ConferenceRSU Research week 2021: Knowledge for Use in Practice
Abbreviated titleRW2021
Country/TerritoryLatvia
CityRīga
Period24/03/2126/03/21
Internet address

Field of Science

  • 3.2 Clinical medicine

Publication Type

  • 3.4. Other publications in conference proceedings (including local)

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