Expression of galanin and the GALR1 galanin receptor subtype in the colon of children with paradoxical fecal incontinence

Arnis Engelis; Dzintars Mozgis; K. A. Pine; J. Shine; T. P. Lismaa; M. Pilmane

doi:10.1111/j.1749-6632.1998.tb10714.x

Expression of galanin and the GALR1 galanin receptor subtype in the colon of children with paradoxical fecal incontinence

Arnis Engelis
, Dzintars Mozgis
, K. A. Pine
, J. Shine
, T. P. Lismaa
, M. Pilmane

Department of Paediatric Surgery

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review

1 Citation (Scopus)

Abstract

Galanin is a 29-30 amino acid peptide originally isolated from porcine upper small intestine and subsequently from a number of vertebrate species.1 Galanin is expressed in the neurons and nerve fibers of the gastrointestinal tract of mammals,2,3 and regulates
ion absorption in ileal tissue4 and the contractile activity of digestive smooth muscle.5–7 Three galanin receptor subtypes have been cloned to date.1 The GALR1 subtype is expressed in the normal human gastrointestinal tract,8 but its expression in diseased gastrointestinal tissue is not known. In this study, we examined the distribution of galaninergic fibers and expression of GALR1 in mucosal epithelial cells in the colon of children with evacuation disorders of the bowel.

Original language	English
Title of host publication	Galanin
Subtitle of host publication	basic research discoveries and therapeutic implications
Editors	T. Hokfelt, T. Bartfai, J. Crawley
Place of Publication	New York
Publisher	New York Academy of Sciences
Pages	425-429
Number of pages	5
Volume	863
DOIs	https://doi.org/10.1111/j.1749-6632.1998.tb10714.x
Publication status	Published - 1998
Event	Conference on Galanin: Basic Research Discoveries and Therapeutic Implications - Stockholm, Sweden Duration: 3 May 1998 → 5 May 1998 https://lib.ugent.be/en/catalog/rug01:000459826

Publication series

Name	Annals of the New York Academy of Sciences
Publisher	Wiley-Blackwell
ISSN (Print)	0077-8923

Conference

Conference	Conference on Galanin: Basic Research Discoveries and Therapeutic Implications
Country/Territory	Sweden
City	Stockholm
Period	3/05/98 → 5/05/98
Internet address	https://lib.ugent.be/en/catalog/rug01:000459826

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Field of Science*

3.2 Clinical medicine
3.1 Basic medicine

Publication Type*

3.1. Articles or chapters in proceedings/scientific books indexed in Web of Science and/or Scopus database

Access to Document

10.1111/j.1749-6632.1998.tb10714.x

https://nyaspubs-onlinelibrary-wiley-com.db.rsu.lv/doi/full/10.1111/j.1749-6632.1998.tb10714.x

Cite this

Engelis, A., Mozgis, D., Pine, K. A., Shine, J., Lismaa, T. P., & Pilmane, M. (1998). Expression of galanin and the GALR1 galanin receptor subtype in the colon of children with paradoxical fecal incontinence. In T. Hokfelt, T. Bartfai, & J. Crawley (Eds.), Galanin: basic research discoveries and therapeutic implications (Vol. 863, pp. 425-429). (Annals of the New York Academy of Sciences). New York Academy of Sciences. https://doi.org/10.1111/j.1749-6632.1998.tb10714.x

Engelis, Arnis ; Mozgis, Dzintars ; Pine, K. A. et al. / Expression of galanin and the GALR1 galanin receptor subtype in the colon of children with paradoxical fecal incontinence. Galanin: basic research discoveries and therapeutic implications. editor / T. Hokfelt ; T. Bartfai ; J. Crawley. Vol. 863 New York : New York Academy of Sciences, 1998. pp. 425-429 (Annals of the New York Academy of Sciences).

@inproceedings{4a06f32175674928b9d713393b731141,

title = "Expression of galanin and the GALR1 galanin receptor subtype in the colon of children with paradoxical fecal incontinence",

abstract = "Galanin is a 29-30 amino acid peptide originally isolated from porcine upper small intestine and subsequently from a number of vertebrate species.1 Galanin is expressed in the neurons and nerve fibers of the gastrointestinal tract of mammals,2,3 and regulates ion absorption in ileal tissue4 and the contractile activity of digestive smooth muscle.5–7 Three galanin receptor subtypes have been cloned to date.1 The GALR1 subtype is expressed in the normal human gastrointestinal tract,8 but its expression in diseased gastrointestinal tissue is not known. In this study, we examined the distribution of galaninergic fibers and expression of GALR1 in mucosal epithelial cells in the colon of children with evacuation disorders of the bowel.",

author = "Arnis Engelis and Dzintars Mozgis and Pine, \{K. A.\} and J. Shine and Lismaa, \{T. P.\} and M. Pilmane",

year = "1998",

doi = "10.1111/j.1749-6632.1998.tb10714.x",

language = "English",

volume = "863",

series = "Annals of the New York Academy of Sciences",

publisher = "New York Academy of Sciences",

pages = "425--429",

editor = "T. Hokfelt and T. Bartfai and J. Crawley",

booktitle = "Galanin",

note = "Conference on Galanin: Basic Research Discoveries and Therapeutic Implications ; Conference date: 03-05-1998 Through 05-05-1998",

url = "https://lib.ugent.be/en/catalog/rug01:000459826",

}

Engelis, A , Mozgis, D, Pine, KA, Shine, J, Lismaa, TP & Pilmane, M 1998, Expression of galanin and the GALR1 galanin receptor subtype in the colon of children with paradoxical fecal incontinence. in T Hokfelt, T Bartfai & J Crawley (eds), Galanin: basic research discoveries and therapeutic implications. vol. 863, Annals of the New York Academy of Sciences, New York Academy of Sciences, New York, pp. 425-429, Conference on Galanin: Basic Research Discoveries and Therapeutic Implications, Stockholm, Sweden, 3/05/98. https://doi.org/10.1111/j.1749-6632.1998.tb10714.x

Expression of galanin and the GALR1 galanin receptor subtype in the colon of children with paradoxical fecal incontinence. / Engelis, Arnis ; Mozgis, Dzintars; Pine, K. A. et al.
Galanin: basic research discoveries and therapeutic implications. ed. / T. Hokfelt; T. Bartfai; J. Crawley. Vol. 863 New York: New York Academy of Sciences, 1998. p. 425-429 (Annals of the New York Academy of Sciences).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review

TY - GEN

T1 - Expression of galanin and the GALR1 galanin receptor subtype in the colon of children with paradoxical fecal incontinence

AU - Engelis, Arnis

AU - Mozgis, Dzintars

AU - Pine, K. A.

AU - Shine, J.

AU - Lismaa, T. P.

AU - Pilmane, M.

PY - 1998

Y1 - 1998

N2 - Galanin is a 29-30 amino acid peptide originally isolated from porcine upper small intestine and subsequently from a number of vertebrate species.1 Galanin is expressed in the neurons and nerve fibers of the gastrointestinal tract of mammals,2,3 and regulates ion absorption in ileal tissue4 and the contractile activity of digestive smooth muscle.5–7 Three galanin receptor subtypes have been cloned to date.1 The GALR1 subtype is expressed in the normal human gastrointestinal tract,8 but its expression in diseased gastrointestinal tissue is not known. In this study, we examined the distribution of galaninergic fibers and expression of GALR1 in mucosal epithelial cells in the colon of children with evacuation disorders of the bowel.

AB - Galanin is a 29-30 amino acid peptide originally isolated from porcine upper small intestine and subsequently from a number of vertebrate species.1 Galanin is expressed in the neurons and nerve fibers of the gastrointestinal tract of mammals,2,3 and regulates ion absorption in ileal tissue4 and the contractile activity of digestive smooth muscle.5–7 Three galanin receptor subtypes have been cloned to date.1 The GALR1 subtype is expressed in the normal human gastrointestinal tract,8 but its expression in diseased gastrointestinal tissue is not known. In this study, we examined the distribution of galaninergic fibers and expression of GALR1 in mucosal epithelial cells in the colon of children with evacuation disorders of the bowel.

UR - https://www.scopus.com/pages/publications/0032438452

U2 - 10.1111/j.1749-6632.1998.tb10714.x

DO - 10.1111/j.1749-6632.1998.tb10714.x

M3 - Conference contribution

C2 - 9928190

AN - SCOPUS:0032438452

VL - 863

T3 - Annals of the New York Academy of Sciences

SP - 425

EP - 429

BT - Galanin

A2 - Hokfelt, T.

A2 - Bartfai, T.

A2 - Crawley, J.

PB - New York Academy of Sciences

CY - New York

T2 - Conference on Galanin: Basic Research Discoveries and Therapeutic Implications

Y2 - 3 May 1998 through 5 May 1998

ER -

Engelis A , Mozgis D, Pine KA, Shine J, Lismaa TP, Pilmane M. Expression of galanin and the GALR1 galanin receptor subtype in the colon of children with paradoxical fecal incontinence. In Hokfelt T, Bartfai T, Crawley J, editors, Galanin: basic research discoveries and therapeutic implications. Vol. 863. New York: New York Academy of Sciences. 1998. p. 425-429. (Annals of the New York Academy of Sciences). doi: 10.1111/j.1749-6632.1998.tb10714.x

Expression of galanin and the GALR1 galanin receptor subtype in the colon of children with paradoxical fecal incontinence

Abstract

Publication series

Conference

UN SDGs

Field of Science*

Publication Type*

Access to Document

Other files and links

Fingerprint

Cite this