Factors affecting facial development and formation of cleft lip and palate: a literature review

Mārtiņš Vaivads (Coresponding Author), Evija Balode, Māra Pilmane

Research output: Contribution to journalArticlepeer-review

1 Downloads (Pure)

Abstract

The craniofacial region forms in a complicated developmental process regu-lated by multiple genes and growth factors. Disruption and dysregulation during facial development can lead to multiple congenital facial anomalies including cleft lip and palate. This literature review collects and analyses the existing information about the interaction of multiple growth factors and genes within the developing facial region and their association with facial pathology. The factors analysed in this review are DLX4, FOXE1, HOXB3, MSX2, PAX7, PAX9, RYK, SHH, SOX3, WNT3A, WNT9B and BARX1.
Original languageEnglish
Pages (from-to)22-35
JournalPapers on Anthropology
Volume29
Issue number2
DOIs
Publication statusPublished - 2020

Keywords*

  • cleft lip
  • cleft palate
  • genes
  • growth factors

Field of Science*

  • 3.1 Basic medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

Fingerprint

Dive into the research topics of 'Factors affecting facial development and formation of cleft lip and palate: a literature review'. Together they form a unique fingerprint.

Cite this