Focused open necrosectomy in necrotizing pancreatitis

Guntars Pupelis, Vladimir Fokin, Kaspars Zeiza, Haralds Plaudis, Anastasija Suhova, Nadezda Drozdova, Viesturs Boka

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)
1 Downloads (Pure)


Background: The control of sepsis is the primary goal of surgical intervention in patients with infected necrosis. Simple surgical approaches that are easy to reproduce may improve outcomes when specialists in endoscopy are not available. The aim of the present study was to describe the experience with abs focused open necrosectomy (FON) in patients with infected necrosis. Method: A prospective pilot study conducted to compare a semi-open/closed drainage laparotomy and FON with the assistance of peri-operative ultrasound. The incidence of sepsis, dynamics of C-reactive protein (CRP), intensive care unit (ICU)/hospital stay, complication rate and mortality were compared and analysed. Results: From a total of 58 patients, 36 patients underwent a conventional open necrosectomy and 22 patients underwent FON. The latter method resulted in a faster resolution of sepsis and a significant decrease in mean CRP on Day 3 after FON, P = 0.001. Post-operative bleeding was in 1 versus 7 patients and the incidence of intestinal and pancreatic fistula was 2 versus 8 patients when comparing FON to the conventional approach. The median ICU stay was 11.6 versus 23 days and the hospital stay was significantly shorter, 57 versus 72 days, P = 0.024 when comparing FON versus the conventional group. One patient died in the FON group and seven patients died in the laparotomy group, P = 0.139. Discussion: FON can be an alternative method to conventional open necrosectomy in patients with infected necrosis and unresolved sepsis.

Original languageEnglish
Pages (from-to)535-540
Number of pages6
Issue number7
Publication statusPublished - 2013
Externally publishedYes

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database


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