TY - CONF
T1 - Fournier gangrene – 10 years’ single centre experience
AU - Bērziņš, Jānis
AU - Rēdmanis, Linards
AU - Dāle, Rolands
AU - Baumanis, Edgars
AU - Auziņš, Jānis
AU - Ļeoņenko, Kļims
AU - Lietuvietis, Vilnis
PY - 2021/3/24
Y1 - 2021/3/24
N2 - Fourniers gangrene (FG) is a severe form of soft tissue infection with a high mortality, that requires agressive treatment and a long recovery. Aim of the study is to identify factors that determine FG patient mortality. 24 patients treated with FG from 2010 to 2020 in Riga East University Hospital were included in this retrospective cohort study. Data was collected on presenting signs, origin of infection, and serum markers of inflammation at time of admission. From this data Fournier gangrene severity index (FGSI) and Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) was calculated for each patient. Secondary points of interest were patient age, time from admission to surgery, number of known risk factors, and treatment outcome. Point-Biserial correlation coefficient was used to determine correlation. Average number of admissions was 2,2 per year. The mean age of presentation was 63 ±12 years, and mortality rate for hospitalisation period was 21%. Age (r = 0.09724, p = 0.65124), FGSI (r = 0.28871, p = 0. 18153) and LRINEC (r = 0. 07834, p = 0. 72894) scores showed no statistically significant correlation with mortality. Two or more risk factors was the only predictor of mortality (OR= 34; CI=3.53 - 474.57; p<0.005). Main prognostic factor for mortality in FG patients is presence of two or more risk factors at presentation. Mortality has significantly decreased in recent years, possibly due to a higher standard of intensive care. Known FG severity scores were not predictive of higher mortality in our patients.
AB - Fourniers gangrene (FG) is a severe form of soft tissue infection with a high mortality, that requires agressive treatment and a long recovery. Aim of the study is to identify factors that determine FG patient mortality. 24 patients treated with FG from 2010 to 2020 in Riga East University Hospital were included in this retrospective cohort study. Data was collected on presenting signs, origin of infection, and serum markers of inflammation at time of admission. From this data Fournier gangrene severity index (FGSI) and Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) was calculated for each patient. Secondary points of interest were patient age, time from admission to surgery, number of known risk factors, and treatment outcome. Point-Biserial correlation coefficient was used to determine correlation. Average number of admissions was 2,2 per year. The mean age of presentation was 63 ±12 years, and mortality rate for hospitalisation period was 21%. Age (r = 0.09724, p = 0.65124), FGSI (r = 0.28871, p = 0. 18153) and LRINEC (r = 0. 07834, p = 0. 72894) scores showed no statistically significant correlation with mortality. Two or more risk factors was the only predictor of mortality (OR= 34; CI=3.53 - 474.57; p<0.005). Main prognostic factor for mortality in FG patients is presence of two or more risk factors at presentation. Mortality has significantly decreased in recent years, possibly due to a higher standard of intensive care. Known FG severity scores were not predictive of higher mortality in our patients.
M3 - Abstract
SP - 251
T2 - RSU Research week 2021: Knowledge for Use in Practice
Y2 - 24 March 2021 through 26 March 2021
ER -