Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up

Sintija Strautmane; Arturs Balodis; Agnete Teivāne; Dagnija Grabovska; Edgars  Naudiņš; Daniels  Urbanovics; Edgars Fišermans; Jānis Mednieks; Alīna Flintere-Flinta; Zanda Priede; Andrejs Millers; Maksims Zolovs

doi:10.3390/medicina59061082

Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up

Sintija Strautmane (Corresponding Author), Arturs Balodis, Agnete Teivāne, Dagnija Grabovska, Edgars Naudiņš, Daniels Urbanovics, Edgars Fišermans, Jānis Mednieks, Alīna Flintere-Flinta, Zanda Priede, Andrejs Millers, Maksims Zolovs

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Abstract

Background and Objectives: We aimed to determine the link between brain volumetry results and functional disability calculated using the Expanded Disability Status Scale (EDSS) among multiple sclerosis (MS) patients in relation to the provided treatment (disease-modifying therapies (DMTs)) during a 5-year follow-up period. Materials and Methods: A retrospective cohort study was performed enrolling 66 consecutive patients with a confirmed diagnosis of MS, predominantly females (62% (n = 41)). Relapsing–remitting (RR) MS was noted in 92% (n = 61) of patients, with the rest being patients with secondary progressive (SP) MS. The mean age was 43.3 years (SD 8.3 years).

Original language	English
Article number	1082
Number of pages	12
Journal	Medicina
Volume	59
Issue number	6
DOIs	https://doi.org/10.3390/medicina59061082
Publication status	Published - 4 Jun 2023

Keywords*

multiple sclerosis
brain atrophy
MRI
EDSS
disability

Field of Science*

3.2 Clinical medicine

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

Access to Document

10.3390/medicina59061082Licence: CC BY

Functional Disability and Brain MRI VolumetryFinal published version, 1.52 MBLicence: CC BY

Cite this

Strautmane, S., Balodis, A., Teivāne, A., Grabovska, D., Naudiņš, E., Urbanovics, D., Fišermans, E., Mednieks, J., Flintere-Flinta, A., Priede, Z., Millers, A., & Zolovs, M. (2023). Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up. Medicina, 59(6), Article 1082. https://doi.org/10.3390/medicina59061082

@article{39692830064d4c6cb13b1e426f9c849a,

title = "Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up",

abstract = "Background and Objectives: We aimed to determine the link between brain volumetry results and functional disability calculated using the Expanded Disability Status Scale (EDSS) among multiple sclerosis (MS) patients in relation to the provided treatment (disease-modifying therapies (DMTs)) during a 5-year follow-up period. Materials and Methods: A retrospective cohort study was performed enrolling 66 consecutive patients with a confirmed diagnosis of MS, predominantly females (62% (n = 41)). Relapsing–remitting (RR) MS was noted in 92% (n = 61) of patients, with the rest being patients with secondary progressive (SP) MS. The mean age was 43.3 years (SD 8.3 years).",

keywords = "multiple sclerosis, brain atrophy, MRI, EDSS, disability",

author = "Sintija Strautmane and Arturs Balodis and Agnete Teivāne and Dagnija Grabovska and Edgars Naudiņ{\v s} and Daniels Urbanovics and Edgars Fi{\v s}ermans and Jānis Mednieks and Alīna Flintere-Flinta and Zanda Priede and Andrejs Millers and Maksims Zolovs",

note = "Funding Information: This research was funded by the Pauls Stradins Clinical University Hospital Scientific Institute Research Grant. Publisher Copyright: {\textcopyright} 2023 by the authors.",

year = "2023",

month = jun,

day = "4",

doi = "10.3390/medicina59061082",

language = "English",

volume = "59",

journal = "Medicina",

issn = "0025-7680",

publisher = "Fundacion Revista Medicina (Buenos Aires)",

number = "6",

}

TY - JOUR

T1 - Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up

AU - Strautmane, Sintija

AU - Balodis, Arturs

AU - Teivāne, Agnete

AU - Grabovska, Dagnija

AU - Naudiņš, Edgars

AU - Urbanovics, Daniels

AU - Fišermans, Edgars

AU - Mednieks, Jānis

AU - Flintere-Flinta, Alīna

AU - Priede, Zanda

AU - Millers, Andrejs

AU - Zolovs, Maksims

PY - 2023/6/4

Y1 - 2023/6/4

N2 - Background and Objectives: We aimed to determine the link between brain volumetry results and functional disability calculated using the Expanded Disability Status Scale (EDSS) among multiple sclerosis (MS) patients in relation to the provided treatment (disease-modifying therapies (DMTs)) during a 5-year follow-up period. Materials and Methods: A retrospective cohort study was performed enrolling 66 consecutive patients with a confirmed diagnosis of MS, predominantly females (62% (n = 41)). Relapsing–remitting (RR) MS was noted in 92% (n = 61) of patients, with the rest being patients with secondary progressive (SP) MS. The mean age was 43.3 years (SD 8.3 years).

AB - Background and Objectives: We aimed to determine the link between brain volumetry results and functional disability calculated using the Expanded Disability Status Scale (EDSS) among multiple sclerosis (MS) patients in relation to the provided treatment (disease-modifying therapies (DMTs)) during a 5-year follow-up period. Materials and Methods: A retrospective cohort study was performed enrolling 66 consecutive patients with a confirmed diagnosis of MS, predominantly females (62% (n = 41)). Relapsing–remitting (RR) MS was noted in 92% (n = 61) of patients, with the rest being patients with secondary progressive (SP) MS. The mean age was 43.3 years (SD 8.3 years).

KW - multiple sclerosis

KW - brain atrophy

KW - MRI

KW - EDSS

KW - disability

UR - http://www.scopus.com/inward/record.url?scp=85163701468&partnerID=8YFLogxK

U2 - 10.3390/medicina59061082

DO - 10.3390/medicina59061082

M3 - Article

SN - 0025-7680

VL - 59

JO - Medicina

JF - Medicina

IS - 6

M1 - 1082

ER -

Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up

Abstract

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Study Findings on Multiple Sclerosis Described by a Researcher at Riga Stradins University (Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up)

Cite this

Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up

Abstract

Keywords*

Field of Science*

Publication Type*

Access to Document

Other files and links

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Study Findings on Multiple Sclerosis Described by a Researcher at Riga Stradins University (Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up)

Cite this