Functional Disability and Brain MRI Volumetry Results among Multiple Sclerosis Patients during 5-Year Follow-Up

Sintija Strautmane (Corresponding Author), Arturs Balodis, Agnete Teivāne, Dagnija Grabovska, Edgars Naudiņš, Daniels Urbanovics, Edgars Fišermans, Jānis Mednieks, Alīna Flintere-Flinta, Zanda Priede, Andrejs Millers, Maksims Zolovs

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Abstract

Background and Objectives: We aimed to determine the link between brain volumetry results and functional disability calculated using the Expanded Disability Status Scale (EDSS) among multiple sclerosis (MS) patients in relation to the provided treatment (disease-modifying therapies (DMTs)) during a 5-year follow-up period. Materials and Methods: A retrospective cohort study was performed enrolling 66 consecutive patients with a confirmed diagnosis of MS, predominantly females (62% (n = 41)). Relapsing–remitting (RR) MS was noted in 92% (n = 61) of patients, with the rest being patients with secondary progressive (SP) MS. The mean age was 43.3 years (SD 8.3 years).

Original languageEnglish
Article number1082
Number of pages12
JournalMedicina
Volume59
Issue number6
DOIs
Publication statusPublished - 4 Jun 2023

Keywords*

  • multiple sclerosis
  • brain atrophy
  • MRI
  • EDSS
  • disability

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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