Abstract
This microreview covers the general methods on the synthesis of mono-, bis-, and tristyrylpyridinium fluorophores described in the literature in recent years. A summary of the most common synthesis can be divided into four distinct methods: aldol condensation followed by N-alkylation of pyridine moiety, Knoevenagel condensation reaction of picolinium salt and aldehyde, Wittig reaction of triphenylphosphine salt and pyridine aldehyde followed by N-alkylation of pyridine moiety, and Horner reaction between bisphosphonate derivative and 4-pyridinecarboxaldehyde followed by N-alkylation of pyridine moiety. Metal-catalyzed reactions were not reviewed. The microreview primary focuses on the synthesis of styrylpyridinium salts having in their structures a 4-pyridinium moiety.
Original language | English |
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Article number | 117377 |
Journal | Chemistry of Heterocyclic Compounds |
DOIs | |
Publication status | E-pub ahead of print - Jan 2025 |
Field of Science*
- 1.4 Chemical sciences
- 3.1 Basic medicine
Publication Type*
- 1.1. Scientific article indexed in Web of Science and/or Scopus database