TY - JOUR
T1 - Glucose metabolism disorders and risk factors of type 2 diabetes in 45-74-years-old population in Riga, Latvia
AU - Barengo, Noël
AU - Misiņa, Dana
AU - Zariņa, Lauma
AU - Kloviņš, Jānis
AU - Ozola, Dita
AU - Derveniece, Andra
AU - Tarasova, Linda
AU - Pirags, Valdis
N1 - Funding Information:
The work was supported by the National Research Programme in Medicine 2006–2009, project No. 14, „Creation of the unified and generally accessible data base on the main life expectancy and life quality threatening pathologies and epidemiology of their risk factors in Latvian population”, and the Finnish Academy Grant. Our personal acknowledgment for their input to the whole team of the study including study coordinators Dita Ozola and Inga Prâne, colleagues from the E. Gulbis laboratory as well as to the colleagues who participated in the initial stage of the project particularly, Ìirts Briìis, Ieva Strçle and Madara Grînðteine.
PY - 2009
Y1 - 2009
N2 - The aims of this study were to investigate the current prevalence of abnormal glucose tolerance (AGT), compare the risk factor profile between persons with and without AGT among 45-74 years-old Latvian men and women, and to validate the Finnish diabetes risk score (FINDRISC) questionnaire in detecting AGT in the middle-aged Latvian population. A cross-sectional survey among the 45-74-years old population randomly selected from the registers of general practitioners in Riga, Latvia was carried out between April 2008 and March 2009. The survey consisted of a questionnaire, measurements such as height, weight, waist circumference, and blood pressure as well as blood oral glucose tolerance test (OGTT), cholesterol and its fractions. Prevalence of obesity, central obesity and physical inactivity were high in the Latvian population. Women with AGT had a worse risk factor profile for T2D and cardiovascular diseases compared to those with normal glucose tolerance. No differences were found in the risk factor profile between men with and without AGT. A high proportion of men and women with more than 11 FINDRISC points had undetected AGT. The FINDRISC questionnaire can be used in clinical practice to detect persons with AGT in the Latvian population.
AB - The aims of this study were to investigate the current prevalence of abnormal glucose tolerance (AGT), compare the risk factor profile between persons with and without AGT among 45-74 years-old Latvian men and women, and to validate the Finnish diabetes risk score (FINDRISC) questionnaire in detecting AGT in the middle-aged Latvian population. A cross-sectional survey among the 45-74-years old population randomly selected from the registers of general practitioners in Riga, Latvia was carried out between April 2008 and March 2009. The survey consisted of a questionnaire, measurements such as height, weight, waist circumference, and blood pressure as well as blood oral glucose tolerance test (OGTT), cholesterol and its fractions. Prevalence of obesity, central obesity and physical inactivity were high in the Latvian population. Women with AGT had a worse risk factor profile for T2D and cardiovascular diseases compared to those with normal glucose tolerance. No differences were found in the risk factor profile between men with and without AGT. A high proportion of men and women with more than 11 FINDRISC points had undetected AGT. The FINDRISC questionnaire can be used in clinical practice to detect persons with AGT in the Latvian population.
KW - Abnormal glucose tolerance
KW - Diabetes
KW - FINDRISC
KW - ROC curve
KW - Screening tool
UR - http://www.scopus.com/inward/record.url?scp=73349102170&partnerID=8YFLogxK
U2 - 10.2478/v10046-009-0049-y
DO - 10.2478/v10046-009-0049-y
M3 - Article
AN - SCOPUS:73349102170
SN - 1407-009X
VL - 63
SP - 141
EP - 146
JO - Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences
JF - Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences
IS - 4-5
ER -