Helicobacter pylori and Inflammatory Bowel Disease: An Unresolved Enigma

Juris Pokrotnieks; Stanislav Sitkin

doi:10.1093/ibd/izac248

Helicobacter pylori and Inflammatory Bowel Disease: An Unresolved Enigma

Juris Pokrotnieks (Coresponding Author), Stanislav Sitkin

Department of Internal Diseases

Research output: Contribution to journal › Article › peer-review

Abstract

The article describes the hypothesis that there may be a noncausal relationship between Helicobacter pylori infection and inflammatory bowel disease (IBD) that is related to the host mucin glycan fucosylation status in the gastrointestinal tract. The proposed hypothesis may explain why IBD is less prevalent in patients with H. pylori, and no increased risk of IBD is seen after H. pylori eradication therapy, as was shown in the study by Tanner et al.

Original language	English
Pages (from-to)	e5-e6
Journal	Inflammatory Bowel Diseases
Volume	29
Issue number	3
DOIs	https://doi.org/10.1093/ibd/izac248
Publication status	Published - Mar 2023

Field of Science*

3.2 Clinical medicine

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

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10.1093/ibd/izac248

Cite this

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abstract = "The article describes the hypothesis that there may be a noncausal relationship between Helicobacter pylori infection and inflammatory bowel disease (IBD) that is related to the host mucin glycan fucosylation status in the gastrointestinal tract. The proposed hypothesis may explain why IBD is less prevalent in patients with H. pylori, and no increased risk of IBD is seen after H. pylori eradication therapy, as was shown in the study by Tanner et al.",

author = "Juris Pokrotnieks and Stanislav Sitkin",

note = "Funding Information: The authors are grateful to Dr James Allen for editing a draft of this manuscript. Publisher Copyright: {\textcopyright} The Author(s) 2022. Published by Oxford University Press on behalf of Crohn{\textquoteright}s & Colitis Foundation. All rights reserved.",

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AU - Sitkin, Stanislav

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N2 - The article describes the hypothesis that there may be a noncausal relationship between Helicobacter pylori infection and inflammatory bowel disease (IBD) that is related to the host mucin glycan fucosylation status in the gastrointestinal tract. The proposed hypothesis may explain why IBD is less prevalent in patients with H. pylori, and no increased risk of IBD is seen after H. pylori eradication therapy, as was shown in the study by Tanner et al.

AB - The article describes the hypothesis that there may be a noncausal relationship between Helicobacter pylori infection and inflammatory bowel disease (IBD) that is related to the host mucin glycan fucosylation status in the gastrointestinal tract. The proposed hypothesis may explain why IBD is less prevalent in patients with H. pylori, and no increased risk of IBD is seen after H. pylori eradication therapy, as was shown in the study by Tanner et al.

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ER -

Helicobacter pylori and Inflammatory Bowel Disease: An Unresolved Enigma

Abstract

Field of Science*

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