HEPATOCYTE GROWTH FACTOR IN MINK LIVER IN CASES OF MYCOSES

Anda Valdovska, A. Jemeljanovs, Māra Pilmane

Research output: Contribution to journalMeeting Abstractpeer-review

Abstract

In the present work we have studied the prevalence of fungal flora in the liver of 18 dark brown minks. We isolated 12 genus of moulds. Members of the genus Candida, Aspergillus and Penicillium were the most frequently isolated strains.
When mink are infected with fungi, the cell recruitment is impaired at the site of the infection, the tissue reaction is highly disorganized in target organs and the infection´s evolution is more severe. We studied HGF expression by immunohistochemistry.
Our results demonstrated that the distribution of hyphae were between hepatocytes in all areas of liver acinus, but fungal blastospores - mainly in interlobular bile ducts. Allocation of
HGF in hepatocytes was observed uniform or non uniform, frequently around bile-ducts and
portal tracts.
In conclusion, detection of HGF simultaneously to inflammation liver might be connected to the tissue ischemia and damage realized by the same inflammatory cells.
Original languageEnglish
Pages (from-to)196-201
JournalVeterinārmedicīnas raksti
Volume2008
Publication statusPublished - 2008
EventInternational Scientific Conference: Animals. Health. Food Hygiene - Jelgava, Latvia
Duration: 14 Nov 2008 → …

Keywords*

  • mink
  • liver
  • mycoses
  • hepatocyte growth factor (HGF)

Field of Science*

  • 3.1 Basic medicine
  • 3.2 Clinical medicine

Publication Type*

  • 3.4. Other publications in conference proceedings (including local)

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