Hybrid Materials based on Silica Nanostructures for Biomedical Scaffolds (Bone Regeneration) and Drug Delivery

Jhaleh Amirian (Coresponding Author), Mojdeh Rahnama Ghahfarokhi

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Silica nanoparticles with nanoporous nature are introduced as thermally and chemically stable nanomaterials with controllable porosity and morphology. The nanoparticles can be divided into three groups: microporous, mesoporous, and macroporous based on the porous size. The use of these materials for different applications is associated with their unique properties as disinfectants. This chapter discusses different synthesis methodologies to prepare well-dispersed mesoporous silica nanoparticles (MSNs) and hollow silica nanoparticles (HSNs) with tunable dimensions ranging from a few to hundreds of nanometers with different mesostructures. Several good characteristics of the MSNs, best biocompatibility and low toxicity, are proposed as the basis of the carrier for the controlled release of drugs, genes into living cells and bone regeneration.
Original languageEnglish
Title of host publicationNanohybrids - Future Materials For Biomedical Applications
EditorsG. Sharma, A. Garcia-Penas
PublisherMaterials Research Forum LLC
Number of pages18
ISBN (Electronic)978-1-64490-107-6
ISBN (Print)978-1-64490-106-9
Publication statusPublished - 20 Jan 2021
Externally publishedYes

Publication series

NameMaterials Research Foundations
ISSN (Print)2471-8890
ISSN (Electronic)2471-8904


  • Silica
  • Sol-Gel
  • Mesoporous
  • Biomedical Applications
  • Drug Delivery

Field of Science*

  • 1.4 Chemical sciences
  • 2.10 Nano-technology
  • 2.5 Materials engineering
  • 3.1 Basic medicine
  • 3.4 Medical biotechnology

Publication Type*

  • 3.2. Articles or chapters in other proceedings other than those included in 3.1., with an ISBN or ISSN code


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