Identification of HTLV-I virus in patients with myelomonocytic leukemia

R. A. Kukain, M. F. Murovska, I. V. Millere, R. A. Vinkele, T. Tkachenko Yu., V. P. Ose, M. K. Pashkute, G. K. Kalnberza, D. V. Grasmane, I. Teilane Ya.

Research output: Contribution to journalArticlepeer-review

Abstract

An association of HTLV-I virus with myelomonocytic leukemia was established by serologic and molecular-biologic procedures. Antibodies to one or two HTLV-I proteins were identified in 10 out of 30 patients with myelomonocytic leukemia; both antibodies to certain HTLV-I proteins and an integrated provirus were detected in 3 cases. Upon examination of donor blood, antibodies to one or two HTLV-I proteins were found in 0.8% cases, but only 0.3% of the examined donors were found positive to HTLV-I. This finding points to the presence of said virus in the population of Latvia.

Original languageEnglish
Pages (from-to)44-49
Number of pages6
JournalVoprosy Onkologii
Volume39
Issue number1-3
Publication statusPublished - 1993
Externally publishedYes

Field of Science*

  • 1.6 Biological sciences
  • 3.1 Basic medicine
  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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