Impact of sintering temperature on the phase composition and antibacterial properties of silver-doped hydroxyapatite

Arita Dubnika, Dagnija Loca, Aigars Reinis, Maris Kodols, Liga Berzina-Cimdina

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

In the present study, the impact of sintering temperature on the phase composition and antibacterial properties of silver-doped hydroxyapatite (HAp/Ag) samples was investigated. HAp/Ag containing 0.2 and 1.2 % silver was prepared using a modified wet chemical precipitation method. The surface morphology and inner structure of the sintered samples were discussed. X-ray powder diffraction (XRD) and scanning electron microscopy (SEM) studies showed that, after the sintering process, HAp/Ag contained a silver oxide phase, which was not observed in raw materials. Phase composition changes at different sintering temperatures were studied, and it was found that silver oxide undergoes phase changes during the sintering process. In vitro antibacterial properties approved the excellent anti-microbial activity of HAp/Ag against the bacterial strains Staphylococcus epidermidis and Pseudomonas aeruginosa. The HAp/Ag sample with 1.2 % silver content, sintered at 1150 °C, showed the highest antibacterial activity.

Original languageEnglish
Pages (from-to)453-462
Number of pages10
JournalPure and Applied Chemistry
Volume85
Issue number2
DOIs
Publication statusPublished - 2013

Keywords*

  • Antimicrobial activity
  • Biomaterials
  • Ceramics
  • Hydroxyapatite
  • Phase transitions
  • Silver

Field of Science*

  • 1.4 Chemical sciences
  • 2.5 Materials engineering
  • 1.6 Biological sciences

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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