Abstract
Background: The proportion of postoperative complications (PC), splenectomies (SP) and blood transfusions (BT) have been described among the indexes of surgical quality in gastric cancer surgery. The aim of this study was to analyze the effect of PC, SP and BT on short- and long-term results of a large cohort of gastric cancer patients.
Methods: Retrospectively collected data from 479 patients who underwent R0 gastrectomy in Latvia Oncology Center from January 1999 to December 2005 were analyzed statistically.
Results: PC were more frequently observed in males (18% vs. 9%; P = 0.005), patients aged ‡68 years (20% vs. 8%; P < 0.001), ASA 3–4 (20% vs. 10%; P = 0.004), tumors requiring a proximal or total gastrectomy (24% vs. 17% vs. 11%; P = 0.089). SP was performed in 33 patients (7%). SP was carried out more frequently in tumors infiltrating the serosa (9% vs. 4%; P = 0.043) and treated by total or proximal gastrectomy (13% vs. 9.5% vs. 2%; P < 0.001). BT were required in 39 patients (8%). BT correlated with male gender (12% vs. 3%; P < 0.001), age ‡68 years (12% vs. 5%; P = 0.007), ASA 3–4 (13% vs. 5%; P = 0.002), proximal or total gastrectomy (19% vs. 13% vs. 4%; P = 0.001). Considering overall long-term results, patients without PC showed a better 5-year survival rate (53% vs. 34%; P = 0.001), as patients without BT (52.5% vs. 28%; P < 0.001) and without SP (52% vs. 36%; P = 0.025).
Conclusions: After excluding postoperative deaths from survival analysis, SP, BT and PC did not affect long-term prognosis.
Methods: Retrospectively collected data from 479 patients who underwent R0 gastrectomy in Latvia Oncology Center from January 1999 to December 2005 were analyzed statistically.
Results: PC were more frequently observed in males (18% vs. 9%; P = 0.005), patients aged ‡68 years (20% vs. 8%; P < 0.001), ASA 3–4 (20% vs. 10%; P = 0.004), tumors requiring a proximal or total gastrectomy (24% vs. 17% vs. 11%; P = 0.089). SP was performed in 33 patients (7%). SP was carried out more frequently in tumors infiltrating the serosa (9% vs. 4%; P = 0.043) and treated by total or proximal gastrectomy (13% vs. 9.5% vs. 2%; P < 0.001). BT were required in 39 patients (8%). BT correlated with male gender (12% vs. 3%; P < 0.001), age ‡68 years (12% vs. 5%; P = 0.007), ASA 3–4 (13% vs. 5%; P = 0.002), proximal or total gastrectomy (19% vs. 13% vs. 4%; P = 0.001). Considering overall long-term results, patients without PC showed a better 5-year survival rate (53% vs. 34%; P = 0.001), as patients without BT (52.5% vs. 28%; P < 0.001) and without SP (52% vs. 36%; P = 0.025).
Conclusions: After excluding postoperative deaths from survival analysis, SP, BT and PC did not affect long-term prognosis.
| Original language | English |
|---|---|
| Pages (from-to) | 383 |
| Number of pages | 1 |
| Journal | Helicobacter |
| Volume | 15 |
| Issue number | 4 |
| Publication status | Published - Aug 2010 |
| Event | XXIIIrd International Workshop on Helicobacter and Related Bacteria in Chronic Digestive Inflammation and Gastric Cancer - Rotterdam, Netherlands Duration: 16 Sept 2010 → 18 Sept 2010 Conference number: 23 |
Field of Science*
- 3.1 Basic medicine
- 3.2 Clinical medicine
Publication Type*
- 3.3. Publications in conference proceedings indexed in Web of Science and/or Scopus database
