Invasive pneumococcal disease and S.pneumoniae carriage in hospitalised children in Latvia 2018-2022

Mareks Marčuks, Hedija Čupeca, Larisa Savrasova, Viktorija Truškova, Pāvels Liepinš, Anna Cimermane, Ilze Grope, Angelika Krūmiņa, Indra Zeltiņa, Juris Ķibilds, Maksims Mukāns

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Abstract

Objectives.
In 2018, 24 663 confirmed cases(6.4 cases per 100 000 population) of invasive pneumococcal disease(IPD) were reported in EU/EEA by 29 countries. Second highest rate were infants
Materials and Methods
Study design- descriptive cross-sectional study. Inpatient statistical data 2018-2022 obtained from Children’s Clinical University Hospital's(CCUH) “Andromeda” database. IPD data of Latvian paediatric population 2018-2022 obtained from Latvian Centre of Disease Prevention and Control(LCDPC). S.pneumoniae DNA obtained from nasopharyngeal and oropharyngeal swabs with further serotyping.
Results.
In CCUH number of acute pneumonias in 2018-2019 were 1049 cases. Severe pneumonia 2.2%(23 cases), of which 8.7% (2) streptococcal. In 2020-2021 were 533 cases of acute pneumonia, 0.5% (3) were severe, 66.6% (2) of them pneumococcal. In 2022 was an increase with 446 acute pneumonia cases- 1.1% (5)severe (60% (3) pneumococcal). In 2018-2022 in CCUH 10 confirmed pneumococcal pneumonia cases. Serotyping done in 2 cases, respectively 23B and 19A.
In 2018-2022 LCDPC data show 18 cases of IPD. Majority 44%(8 cases) in 2020-2021. 33% (6)
Conclusions.
Total number of pneumonia cases during Covid-19 pandemic decreased, however the number of pneumococcal pneumonia cases was the highest in 2020. Total number of IPD cases were evenly high in 2021 and 2022. Most commonly affected age group- children 1-5 years, who should be fully vaccinated against S.pneumoniae. The majority of identified are non-vaccine serotypes(3, 19A).

Original languageEnglish
Pages (from-to)67
JournalMedicina (Kaunas)
Volume59
Issue numberSuppl. 2
Publication statusPublished - 21 Jan 2023
EventRSU Research Week 2023: Research Week 2023 Rīga Stradiņš University - Riga Stradins University, Riga, Latvia
Duration: 27 Mar 202331 Mar 2023
https://rw2023.rsu.lv/general-information
https://rw2023.rsu.lv

Field of Science*

  • 3.3 Health sciences

Publication Type*

  • 3.4. Other publications in conference proceedings (including local)

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