Investigation of biomechanical properties of different elements of human mitral valve

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Mitral valvular heart disease is one of the major causes of morbidity and mortality all over the world. The optimal surgical strategy of treatment of valvular heart disease is repair or replacement. There is still ongoing research for optimal valve replacement options. Creation of new valve prosthesis is still a pressing problem. It is not enough information in publications about biomechanical properties of human mitral valve. We performed experimental studies of biomechanical properties of mitral valves on pathologically unchanged human heart valves, taken from 4 cadaveric hearts. Mitral valve construction elements were investigated using uniaxial tensile tests. It was established that an anterior chordae modulus of elasticity (477.28±2 4.322 MPa), is greater than the one of anterior and posterior leaflet (43.48 ± 15.97 MPa and 6.36 ± 3.15MPa, respectively). These results correspond to previously published reports. Future valve sample radial direction investigations will provide more detailed information about it.

Original languageEnglish
Title of host publication14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2008
PublisherSpringer Verlag
Pages154-155
Number of pages2
ISBN (Print)9783540693666
DOIs
Publication statusPublished - 2008
Event14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics
- Riga, Latvia
Duration: 16 Jun 200820 Jun 2008

Publication series

NameIFMBE Proceedings
Volume20 IFMBE
ISSN (Print)1680-0737

Conference

Conference14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics
Country/TerritoryLatvia
CityRiga
Period16/06/0820/06/08

Keywords

  • anterior leaflet
  • chordae tendineae
  • mitral valve
  • modulus of elastivcity
  • posterior leaflet

Field of Science

  • 2.6 Medical engineering
  • 3.4 Medical biotechnology

Publication Type

  • 3.1. Articles or chapters in proceedings/scientific books indexed in Web of Science and/or Scopus database

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