Investigation of biomechanical properties of different elements of human mitral valve

Janis Pavars; P. Stradins; R. Lacis; I. Ozolanta; V. Kasyanov

doi:10.1007/978-3-540-69367-3_42

Investigation of biomechanical properties of different elements of human mitral valve

Rīga Stradiņš University

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review

Abstract

Mitral valvular heart disease is one of the major causes of morbidity and mortality all over the world. The optimal surgical strategy of treatment of valvular heart disease is repair or replacement. There is still ongoing research for optimal valve replacement options. Creation of new valve prosthesis is still a pressing problem. It is not enough information in publications about biomechanical properties of human mitral valve. We performed experimental studies of biomechanical properties of mitral valves on pathologically unchanged human heart valves, taken from 4 cadaveric hearts. Mitral valve construction elements were investigated using uniaxial tensile tests. It was established that an anterior chordae modulus of elasticity (477.28±2 4.322 MPa), is greater than the one of anterior and posterior leaflet (43.48 ± 15.97 MPa and 6.36 ± 3.15MPa, respectively). These results correspond to previously published reports. Future valve sample radial direction investigations will provide more detailed information about it.

Original language	English
Title of host publication	14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2008
Publisher	Springer Verlag
Pages	154-155
Number of pages	2
ISBN (Print)	9783540693666
DOIs	https://doi.org/10.1007/978-3-540-69367-3_42
Publication status	Published - 2008
Event	14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics - Riga, Latvia Duration: 16 Jun 2008 → 20 Jun 2008 Conference number: 14 https://www.worldcat.org/title/14th-nordic-baltic-conference-on-biomedical-engineering-and-medical-physics-nbc-2008-16-20-june-2008-riga-latvia/oclc/929007847

Publication series

Name	IFMBE Proceedings
Volume	20 IFMBE
ISSN (Print)	1680-0737

Conference

Conference	14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics
Abbreviated title	NBC 2008
Country/Territory	Latvia
City	Riga
Period	16/06/08 → 20/06/08
Internet address	https://www.worldcat.org/title/14th-nordic-baltic-conference-on-biomedical-engineering-and-medical-physics-nbc-2008-16-20-june-2008-riga-latvia/oclc/929007847

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords*

anterior leaflet
chordae tendineae
mitral valve
modulus of elastivcity
posterior leaflet

Field of Science*

2.6 Medical engineering
3.4 Medical biotechnology

Publication Type*

3.1. Articles or chapters in proceedings/scientific books indexed in Web of Science and/or Scopus database

Access to Document

10.1007/978-3-540-69367-3_42

Cite this

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title = "Investigation of biomechanical properties of different elements of human mitral valve",

abstract = "Mitral valvular heart disease is one of the major causes of morbidity and mortality all over the world. The optimal surgical strategy of treatment of valvular heart disease is repair or replacement. There is still ongoing research for optimal valve replacement options. Creation of new valve prosthesis is still a pressing problem. It is not enough information in publications about biomechanical properties of human mitral valve. We performed experimental studies of biomechanical properties of mitral valves on pathologically unchanged human heart valves, taken from 4 cadaveric hearts. Mitral valve construction elements were investigated using uniaxial tensile tests. It was established that an anterior chordae modulus of elasticity (477.28±2 4.322 MPa), is greater than the one of anterior and posterior leaflet (43.48 ± 15.97 MPa and 6.36 ± 3.15MPa, respectively). These results correspond to previously published reports. Future valve sample radial direction investigations will provide more detailed information about it.",

keywords = "anterior leaflet, chordae tendineae, mitral valve, modulus of elastivcity, posterior leaflet",

author = "Janis Pavars and P. Stradins and R. Lacis and I. Ozolanta and V. Kasyanov",

year = "2008",

doi = "10.1007/978-3-540-69367-3\_42",

language = "English",

isbn = "9783540693666",

series = "IFMBE Proceedings",

publisher = "Springer Verlag",

pages = "154--155",

booktitle = "14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2008",

address = "Germany",

note = "14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2008 ; Conference date: 16-06-2008 Through 20-06-2008",

url = "https://www.worldcat.org/title/14th-nordic-baltic-conference-on-biomedical-engineering-and-medical-physics-nbc-2008-16-20-june-2008-riga-latvia/oclc/929007847",

}

Pavars, J , Stradins, P , Lacis, R , Ozolanta, I & Kasyanov, V 2008, Investigation of biomechanical properties of different elements of human mitral valve. in 14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2008. IFMBE Proceedings, vol. 20 IFMBE, Springer Verlag, pp. 154-155, 14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, Riga, Latvia, 16/06/08. https://doi.org/10.1007/978-3-540-69367-3_42

Investigation of biomechanical properties of different elements of human mitral valve. / Pavars, Janis ; Stradins, P.; Lacis, R. et al.
14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2008. Springer Verlag, 2008. p. 154-155 (IFMBE Proceedings; Vol. 20 IFMBE).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review

TY - GEN

T1 - Investigation of biomechanical properties of different elements of human mitral valve

AU - Pavars, Janis

AU - Stradins, P.

AU - Lacis, R.

AU - Ozolanta, I.

AU - Kasyanov, V.

N1 - Conference code: 14

PY - 2008

Y1 - 2008

N2 - Mitral valvular heart disease is one of the major causes of morbidity and mortality all over the world. The optimal surgical strategy of treatment of valvular heart disease is repair or replacement. There is still ongoing research for optimal valve replacement options. Creation of new valve prosthesis is still a pressing problem. It is not enough information in publications about biomechanical properties of human mitral valve. We performed experimental studies of biomechanical properties of mitral valves on pathologically unchanged human heart valves, taken from 4 cadaveric hearts. Mitral valve construction elements were investigated using uniaxial tensile tests. It was established that an anterior chordae modulus of elasticity (477.28±2 4.322 MPa), is greater than the one of anterior and posterior leaflet (43.48 ± 15.97 MPa and 6.36 ± 3.15MPa, respectively). These results correspond to previously published reports. Future valve sample radial direction investigations will provide more detailed information about it.

AB - Mitral valvular heart disease is one of the major causes of morbidity and mortality all over the world. The optimal surgical strategy of treatment of valvular heart disease is repair or replacement. There is still ongoing research for optimal valve replacement options. Creation of new valve prosthesis is still a pressing problem. It is not enough information in publications about biomechanical properties of human mitral valve. We performed experimental studies of biomechanical properties of mitral valves on pathologically unchanged human heart valves, taken from 4 cadaveric hearts. Mitral valve construction elements were investigated using uniaxial tensile tests. It was established that an anterior chordae modulus of elasticity (477.28±2 4.322 MPa), is greater than the one of anterior and posterior leaflet (43.48 ± 15.97 MPa and 6.36 ± 3.15MPa, respectively). These results correspond to previously published reports. Future valve sample radial direction investigations will provide more detailed information about it.

KW - anterior leaflet

KW - chordae tendineae

KW - mitral valve

KW - modulus of elastivcity

KW - posterior leaflet

UR - https://www.scopus.com/pages/publications/78049405940

U2 - 10.1007/978-3-540-69367-3_42

DO - 10.1007/978-3-540-69367-3_42

M3 - Conference contribution

AN - SCOPUS:78049405940

SN - 9783540693666

T3 - IFMBE Proceedings

SP - 154

EP - 155

BT - 14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2008

PB - Springer Verlag

T2 - 14th Nordic-Baltic Conference on Biomedical Engineering and Medical Physics

Y2 - 16 June 2008 through 20 June 2008

ER -

Investigation of biomechanical properties of different elements of human mitral valve

Abstract

Publication series

Conference

UN SDGs

Keywords*

Field of Science*

Publication Type*

Access to Document

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