Kinetic stabilization of amorphous naproxen in its high-drug loaded solid dispersions: impact of the polymer type and after-melt cooling rate

Tetiana Kolisnyk; Valentyn Mohylyuk; G. P.  Andrews

Kinetic stabilization of amorphous naproxen in its high-drug loaded solid dispersions: impact of the polymer type and after-melt cooling rate

Tetiana Kolisnyk
, Valentyn Mohylyuk
, G. P. Andrews

Laboratory of Finished Dosage Forms

Research output: Contribution to conference › Poster › peer-review

17 Downloads (Pure)

Original language	English
Number of pages	1
Publication status	Published - 21 Mar 2024
Event	14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology - Viena, Austria Duration: 18 Mar 2024 → 21 Mar 2024 Conference number: 14th https://www.worldmeeting.org/home/

Meeting

Meeting	14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology
Abbreviated title	PBP
Country/Territory	Austria
City	Viena
Period	18/03/24 → 21/03/24
Internet address	https://www.worldmeeting.org/home/

Keywords*

Amorphous solid dispersions
high-drug loaded
naproxen
polymer
DSC
cooling rate

Field of Science

3.1 Basic medicine
2.4 Chemical engineering
1.4 Chemical sciences
1.3 Physical sciences

Publication Type*

3.4. Other publications in conference proceedings (including local)

Access to Document

2024.03.21. PBP-poster. After-melt cooling (TK)Final published version, 3.85 MB

5 Article

Mechanistic insights into dissolution of highly drug-loaded amorphous solid dispersions of a fast-crystallising drug
Kolisnyk, T. & Mohylyuk, V., Jul 2026, In: European Journal of Pharmaceutics and Biopharmaceutics. 224, 115079.
Research output: Contribution to journal › Article › peer-review

Open Access
High drug-loaded amorphous solid dispersions of a poor glass forming drug: The impact of polymer type and cooling rate on amorphous drug behaviour
Kolisnyk, T., Mohylyuk, V., Fil, N., Bickerstaff, E., Li, S., Jones, D. S. & Andrews, G. P., 10 Feb 2025, In: International Journal of Pharmaceutics. 670, 125095.
Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus)
Quantification of Soluplus for Dissolution Tests: SEC Method Development and Validation
Horvath, Z. M., Lauberte, L. & Mohylyuk, V., Jan 2025, In: Journal of Pharmaceutical Sciences. 114, 1, p. 157-164
Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus)

1 Finished

Preparation of Polymer-Based Amorphous Solid Dispersions of Poorly Soluble Drugs With a Bad Glass-Forming Ability
Mohylyuk, V. (Member of project working group) & Kolisnyk, T. (Member of project working group)
13/03/23 → 30/09/24
Project: Projects not classified elsewhere › Projects outside institution

1 Visiting an external academic institution

Queen's University Belfast
Mohylyuk, V. (Visiting researcher)
21 Oct 2024 → 22 Oct 2024
Activity: Visiting an external institution types › Visiting an external academic institution

Cite this

@conference{1893e736a54a4e649bb146887d0fdbfc,

title = "Kinetic stabilization of amorphous naproxen in its high-drug loaded solid dispersions: impact of the polymer type and after-melt cooling rate",

keywords = "Amorphous solid dispersions, high-drug loaded, naproxen, polymer, DSC, cooling rate",

author = "Tetiana Kolisnyk and Valentyn Mohylyuk and Andrews, \{G. P.\}",

year = "2024",

month = mar,

day = "21",

language = "English",

note = "14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, PBP ; Conference date: 18-03-2024 Through 21-03-2024",

url = "https://www.worldmeeting.org/home/",

}

Kinetic stabilization of amorphous naproxen in its high-drug loaded solid dispersions: impact of the polymer type and after-melt cooling rate. / Kolisnyk, Tetiana; Mohylyuk, Valentyn; Andrews, G. P. .
2024. Poster session presented at 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Viena, Austria.

Research output: Contribution to conference › Poster › peer-review

TY - CONF

T1 - Kinetic stabilization of amorphous naproxen in its high-drug loaded solid dispersions: impact of the polymer type and after-melt cooling rate

AU - Kolisnyk, Tetiana

AU - Mohylyuk, Valentyn

AU - Andrews, G. P.

N1 - Conference code: 14th

PY - 2024/3/21

Y1 - 2024/3/21

KW - Amorphous solid dispersions

KW - high-drug loaded

KW - naproxen

KW - polymer

KW - DSC

KW - cooling rate

M3 - Poster

T2 - 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology

Y2 - 18 March 2024 through 21 March 2024

ER -

Kinetic stabilization of amorphous naproxen in its high-drug loaded solid dispersions: impact of the polymer type and after-melt cooling rate

Meeting

Keywords*

Field of Science

Publication Type*

Access to Document

Research output

Mechanistic insights into dissolution of highly drug-loaded amorphous solid dispersions of a fast-crystallising drug

High drug-loaded amorphous solid dispersions of a poor glass forming drug: The impact of polymer type and cooling rate on amorphous drug behaviour

Quantification of Soluplus for Dissolution Tests: SEC Method Development and Validation

Projects

Preparation of Polymer-Based Amorphous Solid Dispersions of Poorly Soluble Drugs With a Bad Glass-Forming Ability

Activities

Queen's University Belfast

Cite this