Large cell anaplastic lymphoma

LI Yavorkovsky (Coresponding Author), SV Nikulshin, S Leiniece, G Klutse

Research output: Contribution to journalReview articlepeer-review


The review deals with a new variant of non-Hodgkin's lymphoma - large cell anaplastic lymphoma (LCAL). Its history, terminology, ultramicroscopy, phenotype and cytogenetics are discussed. The existing views on the possible role of viruses in the development of LCAL are summarized. The description of clinical forms (cutaneous, with the injury of lymph nodes, mixed, primary and secondary ones, including rare locations) is given. The problems of differential diagnosis, therapy and the data on relatively favourable prognosis are adduced.
Original languageEnglish
Pages (from-to)172-182
Number of pages11
JournalExperimental Oncology
Issue number3
Publication statusPublished - Sept 1995
Externally publishedYes


  • Epstein-Barr virus
  • Diagnosis
  • Large cell anaplastic lymphoma
  • Non-Hodgkin's lymphoma
  • Prognosis
  • Therapy

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database


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