Legionella pneumophila seropositivity-associated factors in latvian blood donors

Olga Valciņa (Coresponding Author), Daina Pūle, Irina Lucenko, Dita Krastiņa, Žanete Šteingolde, Angelika Krūmiņa, Aivars Bērziņš

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Continuous environmental exposure of humans to Legionella may induce immune responses and generation of antibodies. The aim of this study was to investigate the seroprevalence of Legionella pneumophila serogroups (SG) 1–6 in the general healthy population and identify the associated host-related and environmental risk factors. L. pneumophila SG 1–6 seroprevalence among a total of 2007 blood samples collected from healthy donors was 4.8%. Seroprevalence was higher in women (5.9%) than men (3.3%) and in areas with a larger number of inhabitants, ranging from 3.5% in rural regions to 6.8% in the capital, Riga. Blood samples from inhabitants of apartment buildings tested positive for L. pneumophila in more cases (5.8%) compared to those from inhabitants of single-family homes (2.7%). Residents of buildings with a municipal hot water supply system were more likely to be seropositive for L. pneumophila (OR = 3.16, 95% CI 1.26–7.91). Previous episodes of fever were additionally identified as a risk factor (OR = 2.42, 95% CI 1.43–4.1). In conclusion, centralized hot water supply, female gender and previous episodes of fever were determined as the main factors associated with L. pneumophila seropositivity in our study population.

Original languageEnglish
Article number58
JournalInternational Journal of Environmental Research and Public Health
Volume13
Issue number1
DOIs
Publication statusPublished - 22 Dec 2015

Keywords*

  • Blood donors
  • Legionella pneumophila
  • Seroprevalence

Field of Science*

  • 3.3 Health sciences
  • 1.5 Earth and related Environmental sciences

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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