Levofloxacin in veterinary medicine: a literature review

Andrejs Sitovs (Coresponding Author), Irene Sartini, Mario Giorgi

Research output: Contribution to journalReview articlepeer-review

14 Citations (Scopus)


A potent third-generation antimicrobial fluoroquinolone drug, levofloxacin was introduced into human clinical practice in 1993. Levofloxacin is also used in veterinary medicine, however its use is limited: it is completely banned for veterinary use in the EU, and used extralabel in only companion animals in the USA. Since its introduction to clinical practice, many studies have been published on levofloxacin in animal species, including pharmacokinetic studies, tissue drug depletion, efficacy, and animal microbial isolate susceptibility to levofloxacin. This literature overview highlights the most clinically relevant and scientifically important levofloxacin studies linked to the field of veterinary medicine.

Original languageEnglish
Pages (from-to)111-126
Number of pages16
JournalResearch in Veterinary Science
Publication statusPublished - Jul 2021


  • levofloxacin
  • MIC
  • pharmacokinetics
  • review
  • tissue residue

Field of Science*

  • 4.3 Veterinary science

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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