Levofloxacin in veterinary medicine: a literature review

Andrejs Sitovs; Irene Sartini; Mario Giorgi

doi:10.1016/j.rvsc.2021.04.031

Levofloxacin in veterinary medicine: a literature review

Andrejs Sitovs^*
, Irene Sartini
, Mario Giorgi

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

52 Citations (Scopus)

Abstract

A potent third-generation antimicrobial fluoroquinolone drug, levofloxacin was introduced into human clinical practice in 1993. Levofloxacin is also used in veterinary medicine, however its use is limited: it is completely banned for veterinary use in the EU, and used extralabel in only companion animals in the USA. Since its introduction to clinical practice, many studies have been published on levofloxacin in animal species, including pharmacokinetic studies, tissue drug depletion, efficacy, and animal microbial isolate susceptibility to levofloxacin. This literature overview highlights the most clinically relevant and scientifically important levofloxacin studies linked to the field of veterinary medicine.

Original language	English
Pages (from-to)	111-126
Number of pages	16
Journal	Research in Veterinary Science
Volume	137
DOIs	https://doi.org/10.1016/j.rvsc.2021.04.031
Publication status	Published - Jul 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords*

levofloxacin
MIC
pharmacokinetics
review
tissue residue

Field of Science

4.3 Veterinary science

Publication Type*

1.1. Scientific article indexed in Web of Science and/or Scopus database

ASJC Scopus subject areas

General Veterinary

Access to Document

10.1016/j.rvsc.2021.04.031

Cite this

@article{e2978f414507448d98884257da4f9056,

title = "Levofloxacin in veterinary medicine: a literature review",

abstract = "A potent third-generation antimicrobial fluoroquinolone drug, levofloxacin was introduced into human clinical practice in 1993. Levofloxacin is also used in veterinary medicine, however its use is limited: it is completely banned for veterinary use in the EU, and used extralabel in only companion animals in the USA. Since its introduction to clinical practice, many studies have been published on levofloxacin in animal species, including pharmacokinetic studies, tissue drug depletion, efficacy, and animal microbial isolate susceptibility to levofloxacin. This literature overview highlights the most clinically relevant and scientifically important levofloxacin studies linked to the field of veterinary medicine.",

keywords = "levofloxacin, MIC, pharmacokinetics, review, tissue residue",

author = "Andrejs Sitovs and Irene Sartini and Mario Giorgi",

note = "Funding Information: Authors sincerely thank Dr. Victoria Llewelyn (College of Nursing and Health Sciences, Flinders University, Adelaide, Australia) for revision of the manuscript's grammar, and scientific comments. Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd",

year = "2021",

month = jul,

doi = "10.1016/j.rvsc.2021.04.031",

language = "English",

volume = "137",

pages = "111--126",

journal = "Research in Veterinary Science",

issn = "0034-5288",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - Levofloxacin in veterinary medicine

T2 - a literature review

AU - Sitovs, Andrejs

AU - Sartini, Irene

AU - Giorgi, Mario

N1 - Funding Information: Authors sincerely thank Dr. Victoria Llewelyn (College of Nursing and Health Sciences, Flinders University, Adelaide, Australia) for revision of the manuscript's grammar, and scientific comments. Publisher Copyright: © 2021 Elsevier Ltd

PY - 2021/7

Y1 - 2021/7

N2 - A potent third-generation antimicrobial fluoroquinolone drug, levofloxacin was introduced into human clinical practice in 1993. Levofloxacin is also used in veterinary medicine, however its use is limited: it is completely banned for veterinary use in the EU, and used extralabel in only companion animals in the USA. Since its introduction to clinical practice, many studies have been published on levofloxacin in animal species, including pharmacokinetic studies, tissue drug depletion, efficacy, and animal microbial isolate susceptibility to levofloxacin. This literature overview highlights the most clinically relevant and scientifically important levofloxacin studies linked to the field of veterinary medicine.

AB - A potent third-generation antimicrobial fluoroquinolone drug, levofloxacin was introduced into human clinical practice in 1993. Levofloxacin is also used in veterinary medicine, however its use is limited: it is completely banned for veterinary use in the EU, and used extralabel in only companion animals in the USA. Since its introduction to clinical practice, many studies have been published on levofloxacin in animal species, including pharmacokinetic studies, tissue drug depletion, efficacy, and animal microbial isolate susceptibility to levofloxacin. This literature overview highlights the most clinically relevant and scientifically important levofloxacin studies linked to the field of veterinary medicine.

KW - levofloxacin

KW - MIC

KW - pharmacokinetics

KW - review

KW - tissue residue

UR - https://www.scopus.com/pages/publications/85105255801

U2 - 10.1016/j.rvsc.2021.04.031

DO - 10.1016/j.rvsc.2021.04.031

M3 - Review article

C2 - 33964616

AN - SCOPUS:85105255801

SN - 0034-5288

VL - 137

SP - 111

EP - 126

JO - Research in Veterinary Science

JF - Research in Veterinary Science

ER -

Levofloxacin in veterinary medicine: a literature review

Abstract

UN SDGs

Keywords*

Field of Science

Publication Type*

ASJC Scopus subject areas

Access to Document

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Mario Giorgi

Cite this

Levofloxacin in veterinary medicine: a literature review

Abstract

UN SDGs

Keywords*

Field of Science

Publication Type*

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Prizes

Wiley Top Viewed Article

Activities

Mario Giorgi

Cite this