Lipid polymer hybrid as emerging tool in nanocarriers for oral drug delivery

Supandeep Singh Hallan, Prabhjot Kaur, Veerpal Kaur, Neeraj Mishra, Bhuvaneshwar Vaidya

Research output: Contribution to journalReview articlepeer-review

47 Citations (Scopus)

Abstract

The oral route for drug delivery is a widely accepted route. For that reason, many researchers are currently working to develop efficient oral drug delivery systems. Use of polymeric nanoparticles (NPs) and lipid carrier systems, including liposomes, solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLC), has limitations such as drug leakage and high water content of dispersions. Thus, lipid polymer hybrid nanoparticles (LPNs) have been explored by the researchers to provide a better effect using properties of both polymers and lipids. The present review is focused on the challenges, possibilities, and future perspectives of LPNs for oral delivery.

Original languageEnglish
Pages (from-to)334-349
JournalArtificial Cells, Nanomedicine and Biotechnology
Volume44
Issue number1
DOIs
Publication statusPublished - Jan 2016
Externally publishedYes

Keywords*

  • Lipid polymer hybrid nanoparticles
  • Lipids
  • Liposomes
  • Nanoblanket
  • Nanofiber
  • Nanostructured lipid nanoparticles
  • Nanotechnology
  • Polymeric nanoparticles
  • Solid lipid nanoparticles

Field of Science*

  • 1.4 Chemical sciences
  • 3.1 Basic medicine
  • 3.4 Medical biotechnology

Publication Type*

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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