Local Anaesthetics: What Can We Expect More than Pain Relief?

Research output: Contribution to journalArticlepeer-review


This problem–solving article considers positive and negative non-analgesic actions of local anaesthetics, which may play a significant role in patient morbidity and mortality. Direct impact on inflammatory and immune substances and cells leads to antibacterial, anti-inflammatory, immunomodulating and systemic functions of numerous local anaesthetics. Local anaesthetics used perioperatively locally in continuous infusions or in systemic circulation reach and maintain safe and effective rates, but myotoxic and tissue growth-inhibiting effects should be taken in account.
Original languageEnglish
Pages (from-to)100-104
JournalActa Chirurgica Latviensis
Publication statusPublished - 18 Aug 2010


  • Anti-inflammatory
  • immune response
  • local anaesthetic
  • Systemic analgesia
  • Anaesthesiology
  • Anaesthesia

Field of Science*

  • 3.2 Clinical medicine

Publication Type*

  • 1.4. Reviewed scientific article published in Latvia or abroad in a scientific journal with an editorial board (including university editions)


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