@article{a76d6b67775f4689a653f30588d9f8da,
title = "Mepolizumab: Therapeutic strategy for a pediatric patient with eosinophilic granulomatosis with polyangiitis",
abstract = "Eosinophilic granulomatosis with polyangiitis (EGPA; formerly known as Churg-Strauss syndrome) is classified as an antineutrophil cytoplasmic antibody (ANCA)-associated small vessel vasculitis. It is a multisystem disorder and can affect every organ system. EGPA is a rare disease, with an estimated prevalence of 1/70,000–100,000 in Europe. As its onset usually occurs in adulthood, data from pediatric patients are limited. We present here a very rare practical EGPA clinical case involving a pediatric patient. Presently, data on mepolizumab usage in pediatric patients are limited, with only a few case reports published.",
keywords = "mepolizumab in pediatrics, pediatric EGPA, small vessel vasculitis",
author = "Lota Ozola and Elīna Aleksejeva and Diāna Stoldere and Zane Dāvidsone and Ruta {\v S}antere and Ineta Grantiņa and Ieva Cīrule and Alvils Krams",
note = "Funding Information: The authors would like to thank and express their gratitude to the author team for their knowledge, expertise, and enthusiastic work with this clinical case and for their incredible support in creating this paper. The authors also would like to thank the reviewers for their comments that greatly improved the manuscript. We are profoundly grateful and in debt to all frontline healthcare workers for their impressive efforts to tackle the COVID-19 pandemic in Brazil. All data from the SIVEP-Gripe (Influenza Epidemiological Surveillance Information System) were systematically collected in challenging circumstances by these frontline healthcare workers. Publisher Copyright: {\textcopyright} 2022 Wiley Periodicals LLC.",
year = "2023",
month = mar,
doi = "10.1002/ppul.26249",
language = "English",
volume = "58",
pages = "973--979",
journal = "Pediatric Pulmonology",
issn = "8755-6863",
publisher = "John Wiley and Sons Inc.",
number = "3",
}