Metagenomics in ophthalmology: Current findings and future prospectives

Davide Borroni, Vito Romano, Stephen B. Kaye, Tobi Somerville, Luca Napoli, Adriano Fasolo, Paola Gallon, Diego Ponzin, Alfonso Esposito, Stefano Ferrari

    Research output: Contribution to journalReview articlepeer-review

    42 Citations (Scopus)


    Less than 1% of all microorganisms of the available environmental microbiota can be cultured with the currently available techniques. Metagenomics is a new methodology of high-throughput DNA sequencing, able to provide taxonomic and functional profiles of microbial communities without the necessity to culture microbes in the laboratory. Metagenomics opens to a a € hypothesis-free' approach, giving important details for future research and treatment of ocular diseases in ophthalmology, such as ocular infection and ocular surface diseases.

    Original languageEnglish
    Article numbere000248
    JournalBMJ Open Ophthalmology
    Issue number1
    Publication statusPublished - 1 Jun 2019


    • cornea
    • eye
    • metagenomics
    • microbiome
    • ocular surface
    • ophthalmology
    • sequencing

    Field of Science*

    • 3.2 Clinical medicine

    Publication Type*

    • 1.1. Scientific article indexed in Web of Science and/or Scopus database


    Dive into the research topics of 'Metagenomics in ophthalmology: Current findings and future prospectives'. Together they form a unique fingerprint.

    Cite this