Metagenomics in ophthalmology: Current findings and future prospectives

Davide Borroni, Vito Romano, Stephen B. Kaye, Tobi Somerville, Luca Napoli, Adriano Fasolo, Paola Gallon, Diego Ponzin, Alfonso Esposito, Stefano Ferrari

Research output: Contribution to journalReview articlepeer-review

7 Citations (Scopus)

Abstract

Less than 1% of all microorganisms of the available environmental microbiota can be cultured with the currently available techniques. Metagenomics is a new methodology of high-throughput DNA sequencing, able to provide taxonomic and functional profiles of microbial communities without the necessity to culture microbes in the laboratory. Metagenomics opens to a a € hypothesis-free' approach, giving important details for future research and treatment of ocular diseases in ophthalmology, such as ocular infection and ocular surface diseases.

Original languageEnglish
Article numbere000248
JournalBMJ Open Ophthalmology
Volume4
Issue number1
DOIs
Publication statusPublished - 1 Jun 2019
Externally publishedYes

Keywords

  • cornea
  • eye
  • metagenomics
  • microbiome
  • ocular surface
  • ophthalmology
  • sequencing

Field of Science

  • 3.2 Clinical medicine

Publication Type

  • 1.1. Scientific article indexed in Web of Science and/or Scopus database

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