Morphofunctional response of contact tissue to implanted synthetic hydroxyapatite (HAp) ceramic materials saturated with local anesthetic and anti-inflammatory drugs

Ilze Salma, Liga Berzina-Cimdina, Mara Pilmane, Janis Vetra, Girts Salms, Andrejs Skagers

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Besides the main aim of bioceramic as bone substitutes, the seeding of biomaterials with drugs to diminish inflammatory response as pain and swelling is also important. Synthetic hydroxyapatite ceramic tablets were saturated with dexamethasone or lidocaine and implanted subperiostaly on angle of lower jaw of rabbits. Immunohistochemical methods for evaluation of growth factors and apoptosis were applied. Our results may enhance comprehension on reactogenicity of HAp bioceramic implants as bone substitutes in subperiostal environment.

Original languageEnglish
Title of host publicationA Global Road Map for Ceramic Materials and Technologies
Subtitle of host publicationForecasting the Future of Ceramics, International Ceramic Federation - 2nd International Congress on Ceramics, ICC 2008, Final Programme
Number of pages6
Publication statusPublished - 2008
Event2nd International Congress on Ceramics - Verona, Italy
Duration: 29 Jun 20084 Jul 2008
Conference number: 2

Publication series

NameA Global Road Map for Ceramic Materials and Technologies: Forecasting the Future of Ceramics, International Ceramic Federation - 2nd International Congress on Ceramics, ICC 2008, Final Programme

Conference

Conference2nd International Congress on Ceramics
Abbreviated title ICC 2008
CountryItaly
CityVerona
Period29/06/084/07/08

Field of Science

  • 3.1 Basic medicine
  • 3.2 Clinical medicine
  • 2.5 Materials emgineering
  • 2.6 Medical engineering

Publication Type

  • 3.1. Articles or chapters in proceedings/scientific books indexed in Web of Science and/or Scopus database

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